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Patent # Description
US-1,003,6064 Biomolecular sensors and methods
Electronic sensors configured to detect single molecule targets and methods of using and manufacturing such electronic sensors are disclosed. A sensor may...
US-1,003,6063 Method for sequencing a polynucleotide template
A method of determining the sequence of a target nucleic acid is provided. The method can include the steps of (a) performing a defined number of incremental...
US-1,003,6062 Primer middle sequence interference PCR technology
Provided is a primer middle sequence interference PCR method, and the method uses one segment of a non-complemented or same-sequence base of the middle sequence...
US-1,003,6061 Oligonucleotide inhibitor of DNA polymerases
The invention comprises a reversible oligonucleotide inhibitor of nucleic acid polymerases. Methods of designing said inhibitors and using said inhibitors in...
US-1,003,6060 Nucleic acid amplification
The present invention provides methods for the amplification of nucleic acid molecules. Methods for amplifying target polynucleotides, including mRNA, using...
US-1,003,6059 Compositions of toehold primer duplexes and methods of use
Provided herein are primers and primer systems having improved specificity and kinetics over existing primers, and methods of use thereof.
US-1,003,6058 Portable testing device for analyzing biological samples
A portable testing device includes a housing with an integrated touchscreen display and a receptacle in which a sample holder containing a biological sample and...
US-1,003,6057 Recombinase polymerase amplification
This disclosure describes related novel methods for Recombinase-Polymerase Amplification (RPA) of a target DNA that exploit the properties of recombinase and...
US-1,003,6056 Catalytic nucleic acid and gold nanoparticles for detection of biomolecules
The present invention relates to catalytic nucleic acid molecule signal amplification combined with surface plasmon properties of gold nanoparticles to achieve...
US-1,003,6055 Methods for making nucleotide probes for sequencing and synthesis
Compositions and methods for making a plurality of probes for analyzing a plurality of nucleic acid samples are provided. Compositions and methods for analyzing...
US-1,003,6054 Bead beating tube and method for extracting deoxyribonucleic acid and/or ribonucleic acid from microorganisms
The present disclosure provides improved methods for bead beating and a bead beating system useful therefor. The bead beating system comprises a sample tube,...
US-1,003,6053 Determination of variants produced upon replication or transcription of nucleic acid sequences
A method of determining whether or not a nucleic acid having an expected sequence or one or more variants of the expected sequence are present in a sample...
US-1,003,6052 Method for producing biogenic substances
This invention relates to a biogenic substance production process wherein a) at least one starting material has b) at least one enzyme added to it and the...
US-1,003,6051 Enhanced processive cellulases
Nucleic acid sequences encoding chimeric polypeptides that exhibit enhanced cellulase activities are disclosed herein. These nucleic acids may be expressed in...
US-1,003,6050 Cellobiohydrolase variants and polynucleotides encoding same
The present invention relates to cellobiohydrolase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid...
US-1,003,6049 Methods for enhancing the degradation or conversion of cellulosic material
The present invention relates to methods for degrading or converting a cellulosic material and for producing substances from the cellulosic material under high...
US-1,003,6048 Process for obtaining a naphthoquinone derivative from Streptomyces sp
The process for obtaining a naphthoquinone derivative from Streptomyces sp. includes providing a seed inoculum of a strain of Streptomyces sp.; culturing the...
US-1,003,6047 Methods for hydroxylating phenylpropanoids
Provided herein are methods for producing an ortho-hydroxylated phenylpropanoid. In one embodiment the method includes culturing a microbe that includes HpaBC...
US-1,003,6046 Transformed Synechococcus elongatus having capability of producing biodiesel from carbon dioxide and method for...
The present disclosure discloses a transformed Synechococcus elongatus strain capable of producing biodiesel directly from carbon dioxide and a method for...
US-1,003,6045 Method for storing gaseous hydrogen through producing methanoate (formate)
The present invention relates to a method for storing gaseous hydrogen, comprising the steps of producing methanoate (formate) through contacting gaseous...
US-1,003,6044 Genetic engineering of Pseudomonas putida KT2440 for rapid and high yield production of vanillin from ferulic acid
The present invention relates to an improved biocatalytic process for producing vanillin from ferulic acid based on a genetically engineered Pseudomonas...
US-1,003,6043 Processes for producing ethanol and yeast
The present invention relates to processes for producing ethanol from starch-containing material by liquefying the starch-containing material at a temperature...
US-1,003,6042 Method for isomerizing double bonds
A method for isomerizing a double bond is provided. A substrate is exposed to an isomerase enzyme, wherein the isomerase enzyme comprises a redox-regulated...
US-1,003,6041 Method for positioning and integrating transgene and use thereof
Provided in the present invention is a method for positioning and integrating transgene and a use thereof. Specifically provided is a variant loxP element. The...
US-1,003,6040 Methods and compositions for the activation of gamma-delta T-cells
The present invention relates generally to methods and compositions for gene therapy and immunotherapy that activate gamma delta T-cells, and in particular, can...
US-1,003,6039 Cocal vesiculovirus envelope pseudotyped retroviral vectors
Provided herein are Cocal vesiculovirus envelope pseudotyped retroviral vectors that exhibit high titers, broad species and cell-type tropism, and improved...
US-1,003,6038 HIV pre-immunization and immunotherapy
The present invention relates generally to immunization and immunotherapy for the treatment or prevention of HIV. In particular, the methods include in vivo...
US-1,003,6037 Insect inhibitory proteins
Pesticidal proteins exhibiting toxic activity against Coleopteran and Lepidopteran pest species are disclosed, and include, but are not limited to, TIC2421...
US-1,003,6036 Compositions and methods for deploying a transgenic refuge as a seed blend
Methods and compositions for deploying refuge seeds together with transgenic crop seeds are provided. The refuge seeds can be non-transgenic seeds of a similar...
US-1,003,6035 Methods and means of increasing the water use efficiency of plants
The invention relates to methods of producing a desired phenotype in a plant by manipulation of gene expression within the plant. The method relates to means...
US-1,003,6034 Sequences involved in plant yield and methods of using
Nucleic acid sequences involved in plant yield are provided, as are methods of using such nucleic acid sequences.
US-1,003,6033 Method of inhibiting sprouting in plant tissues
The present invention relates to a method for inhibiting sprouting, particularly pre-harvest sprouting, in plant seeds, by introducing a polynucleotide encoding...
US-1,003,6032 Methods and compositions for watermelon firmness
The invention provides for unique watermelon plants with an ultra-firm flesh phenotype and their progeny. Such plants may comprise an introgressed QTL...
US-1,003,6031 Polynucleotides, polypeptides and methods for increasing oil content, growth rate and biomass of plants
Provided are method of increasing oil content, growth rate, biomass, yield and/or vigor of a plant. The methods are effected by upregulating in the plant an...
US-1,003,6030 Use of the soybean sucrose synthase promoter to increase plant seed lipid content
Recombinant DNA constructs comprising the soybean sucrose synthase promoter operably linked to polynucleotides encoding transcription factors such as ODP1, Lec1...
US-1,003,6029 Molecular markers for low palmitic acid content in sunflower (Helianthus annus), and methods of using the same
This disclosure concerns methods and compositions for identifying sunflower plants that have a low palmitic acid content phenotype. Some embodiments concern...
US-1,003,6028 Maize ubiquitin promoters
The Zea mays c.v. B73 Ubiquitin-1 (Z. mays c.v. B73 Ubi-1) promoter drives high levels of constitutive transgene expression in plants. Repeated use of the same...
US-1,003,6027 Soybean variety 01064536
The invention relates to the soybean variety designated 01064536. Provided by the invention are the seeds, plants and derivatives of the soybean variety...
US-1,003,6026 Methods for dynamic vector assembly of DNA cloning vector plasmids
A method for using cloning vector plasmids to produce DNA molecules, such as transgenes, in a single cloning step. The transgenes can be used for the purpose of...
US-1,003,6025 Oligonucleotide compositions with enhanced efficiency
The oligonucleotide compositions of the present invention make use of combinations of oligonucleotides. In one aspect, the invention features an oligonucleotide...
US-1,003,6024 siRNA compositions that specifically downregulate expression of a variant of the PNPLA3 gene and methods of use...
The invention provides siRNA compositions that specifically downregulates expression of a variant of the PNPLA3 gene and methods of use thereof for treating a...
US-1,003,6023 Treatment of disease by modulation of SIRT6
An aspect of an embodiment of the invention relates to providing treatment of disease, in particular age-related disease, through increasing or decreasing the...
US-1,003,6022 Antisense oligonucleotides (ODN) against Smad7 and uses thereof in medical field
The invention relates to antisense oligonucleotidic sequences (ODN) against Smad7 suitably modified, and their uses in medical field as therapeutic biological...
US-1,003,6021 5' triphosphate oligonucleotide with blunt end and uses thereof
The present invention provides an oligonucleotide which is capable of activating RIG-I and inducing an anti-viral, in particular, an IFN, response in cells...
US-1,003,6020 Compositions and methods for inhibiting JC virus (JCV)
The instant invention provides compositions and methods for inhibiting the JC Virus (JCV), and that can be used, for example, for treating progressive...
US-1,003,6019 Bicyclic carbocyclic nucleosides and oligomeric compounds prepared therefrom
The present invention provides novel bicyclic carbocyclic nucleosides and oligomeric compounds prepared therefrom. Incorporation of one or more of the bicyclic...
US-1,003,6018 Compositions and methods for treating cachexia
The present invention relates, in various embodiments, to methods of treating cachexia (e.g., cancer cachexia) in a patient. The methods comprise administering...
US-1,003,6017 Methods and compositions for the specific inhibition of complement component 5(C5) by double-stranded RNA
This invention relates to compounds, compositions, and methods useful for reducing C5 target RNA and protein levels via use of dsRNAs, e.g., Dicer substrate...
US-1,003,6016 Methods for inducing glucose uptake
The present invention provides a method for inducing glucose uptake in a muscle cell by inhibiting Trim32 protein in the cell and to a method for inducing...
US-1,003,6015 Composition and methods for reduced scarring and treatment of fibrosis
Embodiments of the present disclosure are directed to methods of treating, reducing or preventing fibrosis or scarring including administering a therapeutic...
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