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Patent # Description
US-1,003,4947 Formulations containing clopidogrel and sulfoalkyl ether cyclodextrin and methods of use
The present invention provides compositions containing clopidogrel, present as a free base or a pharmaceutically acceptable salt thereof, and sulfoalkyl ether...
US-1,003,4946 Odor free milk production enhancers for ruminants
A feed supplement for ruminants to increase milk production, comprised of a carrier and the reaction product of a water soluble polycarboxylic acid, a metal...
US-1,003,4945 Silk powder compaction for production of constructs with high mechanical strength and stiffness
The present disclosure relates generally to compositions and methods for production of three-dimensional constructs with high mechanical strength and/or stiffness.
US-1,003,4944 Wound healing using topical systems and methods
The present invention generally relates to compositions and methods for topical or transdermal delivery and treatment of wounds and/or promoting wound healing....
US-1,003,4943 Sprayable topical carrier and composition comprising phosphatidylcholine
A pharmaceutical or cosmetic carrier for topical administration substantially consists of phosphatidylcholine, monoglyceride, fatty acid ester of...
US-1,003,4942 Stabilized hypohalous acid solutions
The present invention provides a stabilized hypohalous acid solution (or formulation thereof), which may be conveniently packaged for sale, or stored for later...
US-1,003,4941 Iron-salen complex
The present invention provides a drug delivery system that overcomes conventional technical problems and that is readily put to practical use. Iron-salen...
US-1,003,4940 High concentration antibody and protein formulations
The present application relates to highly concentrated antibody and protein formulations with reduced viscosity that are stable, relatively isotonic and are of...
US-1,003,4939 Synergistic combination of immunologic inhibitors for the treatment of cancer
In some embodiments, the methods involve the use of a combination of at least two of the following: an inhibitor of indoleamine-2,3-dioxygenase (IDO), an...
US-1,003,4938 Method for treating melanoma using a herpes simplex virus and an immune checkpoint inhibitor
The invention relates to methods of treating melanoma using a herpes simplex virus in combination with an immune checkpoint inhibitor.
US-1,003,4937 Synergistic nutritional compositions and uses thereof
Provided are nutritional compositions comprising a combination of a probiotic, dietary butyrate and/or a component for stimulating butyrate production in the...
US-1,003,4936 Method of inducing a cross-reactive HIV-1 immune response by administering a composition comprising the GBV-C...
GB virus C (GBV-C or hepatitis G virus) is a flavivirus that frequently leads to chronic viremia in humans. The invention provides compositions and methods...
US-1,003,4935 Neuroattenuated herpes simplex virus
A mutant HSV-1 (referred to herein as KOS-NA) was generated. KOS-NA contains novel mutations in the UL39 gene, which encodes for a protein that is a large...
US-1,003,4934 Porcine epidemic diarrhea virus vaccines and methods of use thereof
The present disclosure provides an isolated or purified Porcine Epidemic Diarrhea Virus (PEDV) or Porcine Epidemic Diarrhea Virus (PEDV) S1 protein, and methods...
US-1,003,4933 HIV and immunogenic peptide sequences and compositions
The present specification discloses an immunogenic composition comprising polypeptide, wherein each of the polypeptides has no more than 100 amino acids, which...
US-1,003,4932 H3 influenza A virus
The invention provides an isolated H3 equine influenza A virus, as well as methods of preparing and using the virus, and genes or proteins thereof.
US-1,003,4931 Use of EGFR pathway inhibitors to increase immune responses to antigens
This disclosure relates to using EGFR pathway inhibitors in combination with compositions comprising an antigen to increase, elicit, or improve an antigen or...
US-1,003,4930 Filovirus consensus antigens, nucleic acid constructs and vaccines made therefrom, and methods of using same
Nucleic acid molecules and compositions comprising one or more nucleic acid sequences that encode a consensus filovirus immunogen including a consensus...
US-1,003,4929 RNA interference functions as an antiviral immunity in mammals
The disclosure provides recombinant viral vectors and attenuated viruses and viral vaccines comprising a virus lacking a functional viral RNA suppressor of host...
US-1,003,4928 Proteins and nucleic acids useful in vaccines targeting Staphylococcus aureus
Disclosed are novel immunogenic proteins derived from Staphylococcus aureus, as well as methods for their use in conferring protective immunity against S....
US-1,003,4927 Methods and compositions relating to synthetic beta-1,6 glucosamine oligosaccharides
The invention relates to the compositions of synthetic oligo-.beta.-(1.fwdarw.6)-2-amino-2-deoxy-D-glu-copyranosides conjugated to carriers, and methods for...
US-1,003,4926 Use of toll-like receptor agonist for treating cancer
The present invention is directed to methods and agents used for treating cancer in Toll-Like Receptor 5-expressing tissues by providing a Toll-Like Receptor...
US-1,003,4925 Modified natural killer cells and natural killer cell lines having increased cytotoxicity
NK cells and NK cell lines are modified to increase cytotoxicity, wherein the cells and compositions thereof have a use in the treatment of cancer. Production...
US-1,003,4924 Methods and compositions for enhanced cellular selectivity using nanocarrier-associated ligands
The presently disclosed subject matter provides methods and compositions for activation of clustered receptors on a target cell using nanocarrier-associated...
US-1,003,4923 Methods for treatment of incontinence associated with sexual activity
The invention provides compositions and methods for treating incontinence associated with sexual activity.
US-1,003,4922 Peptide having angiogenesis inhibitory activity and composition containing same
A peptide having angiogenesis inhibition activity and pharmaceutical composition comprising thereof is described. More specifically, the application relates to...
US-1,003,4921 Proteins with modified glycosylation and methods of production thereof
In one aspect, the disclosure provides proteins with modified glycosylation and methods of their production. In aspect, the disclosure provides transgenic...
US-1,003,4920 Method of treatment and agents useful for same
The present invention relates generally to a method of modulating graft functionality. More specifically, the present invention relates to a method of...
US-1,003,4919 Targeted human-interferon fusion proteins
This disclosure relates to a modified .alpha.-helical bundle cytokine, with reduced activity via an .alpha.-helical bundle cytokine receptor, wherein the...
US-1,003,4918 Therapeutic use of a growth factor, METRNL
The present invention relates to the field of therapeutic use of proteins, genes and cells, in particular to the therapy based on the biological function of a...
US-1,003,4917 Nanoparticle-mediated delivery of cytokines for maintenance of the regulatory T cell phenotype
Compositions for delivery of growth factors needed for stable Tregs and methods of use thereof are provided. In preferred embodiments, the compositions can...
US-1,003,4916 Methods of treating a retinal disease by retinal pigment epithelial stem cells
The present invention relates to a retinal pigment epithelial stem cell isolated from a posterior region of the retinal pigment epithelium of an adult mammal....
US-1,003,4915 Small heat shock proteins and active fragments thereof as a therapy for inflammation and ischemia
The invention provides methods for treating inflammatory diseases by administering to the subject an effective amount of specific peptides derived from HSPB5,...
US-1,003,4914 Brain and neural treatments comprising peptides and other compositions
The present invention generally relates to compositions and methods for treatment of subjects in need of muscle growth, muscle repair, improved muscular and...
US-1,003,4913 Anti-angiogenic peptides and uses thereof
Provided are peptide sequences derived from prostate serum antigen (PSA). The peptides are provided in cyclic and linear form. Methods for using the peptides...
US-1,003,4912 SMAC Mimetic
A SMAC mimetic and pharmaceutical compositions thereof and methods of use.
US-1,003,4911 Chondrocyte proliferation promoting agent
The present invention provides a novel active ingredient which can be safely used in preventing, ameliorating or treating diseases related to the cartilage such...
US-1,003,4910 Chardonnay grape seed extract
A novel grape seed extract is enriched in procyanidins, has total polyphenols of less than 70%, and has a low degree of polymerization (dp). Other fractions of...
US-1,003,4909 Antiobesity agent containing walnut extract
To provide an antiobesity agent. An antiobesity agent containing an extract of walnut branches, shells, or leaves as an active ingredient.
US-1,003,4908 Treatment of virus-based diseases of the skin
A method for treatment of virus-based diseases of the skin, in particular, herpes simplex virus type-1 and herpes zoster, which comprises topically...
US-1,003,4907 Flavored and edible cannabinoid composition and method of manufacturing
A flavored cannabinoid composition and method of manufacturing. The cannabinoid composition includes a cannabis resin, a solvent, such as propylene glycol, and...
US-1,003,4906 Polysaccharides from prasinococcales
There is provided a composition comprising a polysaccharide obtainable from the microalgae, Prasinococcus capsulatus and strains related to P. capsulatus for...
US-1,003,4905 Group B adenovirus modified in the E4orf4 region
The present disclosure relates to a type B adenovirus wherein E4orf4 is deleted or non-functional and generally having a DNA sequence in the E3 region, in...
US-1,003,4904 Methods and compositions of biocontrol of plant pathogens
The present invention comprises methods and composition for control of plant pathogens. Isolated bacteria, deposited with ATCC under the Budapest Treaty, are...
US-1,003,4903 Bacterium-based microrobot capable of targeting cancer tissue
To provide a bacterium-based microrobot which can be specifically targeted to cancer in vivo, the present invention provides a drug delivery system for cancer...
US-1,003,4902 MicroRNAs for the generation of astrocytes
A method of generating a population of cells useful for treating a nerve disease or disorder in a subject, the method comprising up-regulating a level of at...
US-1,003,4901 Cancer immunotherapy
Methods of providing populations of NKT and/or .gamma..delta. T cells, and their use, e.g., in therapies such as cancer immunotherapy.
US-1,003,4900 Method of producing myeloid blood cells
An object of the present invention is to provide a method of producing a myeloid blood cell possessing a proliferative capability. According to the present...
US-1,003,4899 Solid oral dosage form for breast symptoms
The invention is a solid oral dosage form that is designed to deliver a supraphysiological dose of molecular iodine of 3 to 60 mg per day. The solid oral dosage...
US-1,003,4898 Methods and systems for treatment of inflammatory diseases with nitric oxide
The present invention generally relates to compositions and methods for treatment of various inflammatory diseases, such as inflammatory dermatoses and other...
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