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Patent # Description
US-1,003,9760 Method of using diketopiperazines and composition containing them
The invention provides a method of inhibiting the effects of platelet activating factor (PAF). For instance, a disease or condition mediated by PAF...
US-1,003,9759 Quinolines as FGFR kinase modulators
The invention relates to new quinoline derivative compounds of formula (I), to pharmaceutical compositions comprising said compounds, to processes for the...
US-1,003,9758 Compositions and methods for inhibiting bacterial and viral pathogens
Compositions and methods including Amodiaquine (AQ) or N-Desethy Amodiaquine (DEAQ) are provided for treating, inhibiting, or preventing cathepsin B dependent...
US-1,003,9757 C-Met modulator pharmaceutical compositions
Pharmaceutical compositions and unit dosage forms comprising Compound I are disclosed. ##STR00001##
US-1,003,9756 Reducing memory loss in mammals suffering from alzheimer's disease
The disclosure relates to methods and compositions for reducing memory loss. Specifically, methods of using inhibitors of GAT-3 polypeptide activity to reduce...
US-1,003,9755 2-(azaindol-2-yl) benzimidazoles as PAD4 inhibitors
Compounds of formula (I) wherein; R.sub.1 is hydrogen or C.sub.1-6alkyl; R.sub.2 is hydrogen, C.sub.1-6alkyl, perhalomethylC.sub.0-5alkyl-O--, or ...
US-1,003,9754 Anti-viral compounds
Compounds effective in inhibiting replication of Hepatitis C virus ("HCV") are described. This invention also relates to processes of making such compounds,...
US-1,003,9753 Imidazo[4,5-c]quinoline and imidazo[4,5-c][1,5]naphthyridine derivatives as LRRK2 inhibitors
The present invention provides novel imidazo[4,5-c]quinoline and imidazo[4,5-c][1,5]naphthyridine derivatives of Formula (I), and the pharmaceutically...
US-1,003,9752 Methazolamide for the treatment of cancer
The present invention relates to methods of using methazolamide to treat pancreatic cancer. Pancreatic cancer can be treated by administering to a patient in...
US-1,003,9751 Reversing intestinal inflammation by inhibiting retinoic acid metabolism
An agent that increases local concentration of retinoic acid (RA) in the intestine through modifying enzymatic pathways involved in RA metabolism is...
US-1,003,9750 Solid forms of bendamustine hydrochloride
Novel solid forms of bendamustine hydrochloride are described, as well as methods of their preparation and use.
US-1,003,9749 Substituted pyrazole derivatives
A substituted pyrazole derivative includes a compound of the formula: ##STR00001## or a pharmaceutically acceptable salt thereof.
US-1,003,9748 PRMT1 inhibitors and uses thereof
Described herein are compounds of Formula (I-a) and (I-b), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the...
US-1,003,9747 Tetrahydrocyclopentapyrrole derivatives and a method for preparing the same
The present invention provides tetrahydrocyclopentapyrrole derivatives that can be used for preventing or treating peptic ulcer, gastritis or reflux...
US-1,003,9746 1-aryl-3-azabicyclo[3.1.0]hexanes: preparation and use to treat neuropsychiatric disorders
The invention provides novel, multiply-substituted 1-aryl-3-azabicyclo[3.1.0]hexanes, and related processes and intermediates for preparing these compounds, as...
US-1,003,9745 Enalapril formulations
Provided herein are stable enalapril oral liquid formulations. Also provided herein are methods of using enalapril oral liquid formulations for the treatment of...
US-1,003,9744 Post nerve injury rehabilitation effect-enhancing agent comprising alkyl ether derivative or salt thereof
Provided is a medicinal composition characterized by comprising an alkyl ether derivative represented by general formula [1] ##STR00001## [wherein: R.sup.1 and...
US-1,003,9743 Method of treating presbyopia using dithiol compounds and their derivatives
Dithiol compounds and derivatives thereof are disclosed. The agents are useful for treating ocular disease, especially presbyopia and cataract.
US-1,003,9742 Sn-2-monoacylglycerols and lipid malabsorption
The present invention relates generally to the field of lipids and in particular aims at improving lipid absorption, for example under conditions of lipid...
US-1,003,9741 Use of delta tocopherol for the treatment of lysosomal storage disorders
This disclosure relates generally to the treatment of lysosomal storage disorders. Specifically, the disclosure relates to a novel use of .delta. tocopherol in...
US-1,003,9740 Therapeutic combinations of sesquiterpenes and flavonoids
Provided is a pharmaceutical formulation and a method associated therewith for treating inflammation. The pharmaceutical formulation includes therapeutically...
US-1,003,9739 Nanoparticle isoflavone compositions and methods of making and using the same
The present invention is directed to formulations of genistein and methods for making and using the same. In particular embodiments, the formulations described...
US-1,003,9738 Ulcer treatment
The present invention relates to the treatment of peptic ulcers. In particular, the present invention provides methods and compositions for the treatment of...
US-1,003,9737 Multi-arm polymeric alkanoate conjugates
Among other aspects, provided herein are multi-armed polymer conjugates comprising an alkanoate-linker, compositions comprising such conjugates, and related...
US-1,003,9736 Method for transnasal delivery of blood-brain barrier permeation agent and therapeutic agent
Described herein is a method for treating a central nervous system disorder, said method comprising steps of first transnasally administering to or immediately...
US-1,003,9735 Treatment of diseases associated with hepatic stellate cell activation using ammonia-lowering therapies
Disclosed herein are methods of preventing, treating, and delaying the onset or progression of diseases associated with hepatic stellate cells (HSCs), such as...
US-1,003,9734 Eicosapentaenoic acid (EPA) formulations
Provided herein are compositions comprising eicosapentaenoic acid (EPA) and polar lipids (e.g., glycolipids and phospholipids), and which do not contain any...
US-1,003,9733 Compositions, method, and kits for treating pulmonary conditions
Compositions, methods, and kits useful for treating pulmonary conditions are provided herein. Such compositions can contain synergizing amounts of a...
US-1,003,9732 Nutritional composition for improving brain function in phenylketonuria
The present invention relates to food compositions comprising nutritional composition for use in the treatment or nutritional management of phenylketonuria or...
US-1,003,9731 Treatment of cancer with specific RXR agonists
A method of treating cancer is disclosed comprising administering to a patient in need of such treatment a RXR agonist at a level below the RAR activating...
US-1,003,9730 Sorbic and benzoic acid and derivatives thereof enhance the activity of a neuropharmaceutical
Methods and compositions are provided for treating neuropsychiatric disorders such as schizophrenia, depression, attention deficit disorder, mild cognitive...
US-1,003,9729 Use of kukoamine A and kukoamine B
The use of Kukoamine A and Kukoamine B in the preparation of drugs for the prevention and treatment of sepsis and autoimmune disease is disclosed. Bacterial...
US-1,003,9728 More potent and less toxic formulations of epinephrine and methods of medical use
The present invention provides pharmaceutical formulations of levorotatory-epinephrine, 1-epinephrine, more potent and less toxic than existing pharmaceutical...
US-1,003,9727 Adamantane or pinene derivatives for use in the treatment of chlamydiales infections
The present invention relates to a method for treating a Chlamydiales infection comprising the administration of a therapeutically effective amount of a...
US-1,003,9726 Identification of stabilizers of multimeric proteins
Disclosed herein are compounds and compositions thereof which find use in increasing stability of TTR tetramers reducing its tendency to misfold and form...
US-1,003,9725 Method for treating non-melanoma skin cancer by inducing UDP-glucuronosyltransferase activity using pterostilbene
A method is provided for treating an individual for a cellular proliferative disorder, including administering to the individual in need of such treatment a...
US-1,003,9724 7-hydroxy cannabidiol (7-OH-CBD) for use in the treatment of non-alcoholic fatty liver disease (NAFLD)
The liver plays a key role in regulating total body energy homeostasis and its ability to do so is greatly affected by the occurrence of pathological conditions...
US-1,003,9723 Onychomycosis treatment system and method
A system and method includes delivery of a redox gas solution to treat onychomycosis, wherein the redox gas solution comprises a reactive species dissolved in a...
US-1,003,9722 Treatment of oxidative stress disorders including contrast nephropathy, radiation damage and disruptions in the...
Methods of treating or suppressing oxidative stress diseases and symptoms related to oxidative stress affecting normal electron flow in the cells or caused by...
US-1,003,9721 Dressing for promotion of wound healing
A dressing includes a silk protein layer and a hydrophilic glycoside compound, and the hydrophilic glycoside compound is coated on the silk protein layer....
US-1,003,9720 Tamper resistant dosage form comprising co-extruded, adverse agent particles and process of making same
The present invention relates to co-extruded pharmaceutical compositions and dosage forms comprising an adverse agent, such as an opioid antagonist, which can...
US-1,003,9719 Methods of treating attention deficit hyperactivity disorder
The invention is directed to oral modified/controlled release drug formulations which provide a rapid initial onset of effect and a prolonged duration of...
US-1,003,9718 Use of solid carrier particles to improve the processability of a pharmaceutical agent
The invention provides a composition comprising, a compound of formula (I): ##STR00001## or a pharmaceutically acceptable salt thereof and a plurality of...
US-1,003,9717 Method of preparing biologically active formulations
The invention provides pellet for use as a core for a pharmaceutical dosage form having an inner and an outer zone where the inner zone includes a biologically...
US-1,003,9716 Liposomal cisplatin compositions for cancer therapy
The present invention provides a composition for the treatment of cancer including zwitterionic liposomes consisting essentially of: 50-65 mol % of a...
US-1,003,9715 Liposomal formulation of nonglycosidic ceramides and uses thereof
The invention provides liposomes containing nonglycosidic ceramides within their bilayers, and compositions thereof. These liposomes activate murine iNKT cells...
US-1,003,9714 Imino compounds for amphoteric liposomes and uses thereof
The invention concerns lipid assemblies, liposomes having an outer surface comprising a mixture of anionic and cationic moieties; wherein at least a portion of...
US-1,003,9713 Drug-loaded ganglioside micelle and the preparation method and use thereof
The present application belongs to the field of biopharmaceutical technology and particularly relates to a drug-loaded ganglioside micelle and a method for...
US-1,003,9712 Racecadotril lipid compositions
The present invention is drawn to a pharmaceutical composition comprising racecadotril, at least one surfactant and a lipid. The pharmaceutical composition is...
US-1,003,9711 Self-adhesive film for teeth
Monolayered or multilayered, film-shaped, pressure-sensitive adhesive preparations for application in the oral region and a process for manufacturing such...
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