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Patent # Description
US-1,003,9782 Onychomycosis treatment apparatus and method
A system and method includes delivery of a redox gas solution to treat onychomycosis, wherein the redox gas solution comprises a reactive species dissolved in a...
US-1,003,9781 Pulse inhalation of nitric oxide for treating respiratory diseases
A method of treating a human subject which is effected by intermittent breathing cycle-coordinated pulse delivery inhalation of gaseous nitric oxide at a...
US-1,003,9780 Pharmaceutical formulations comprising high purity cangrelor and methods for preparing and using the same
The present invention relates to high purity cangrelor, pharmaceutical formulations comprising high purity cangrelor as an active ingredient, methods for...
US-1,003,9779 Combination formulation of two antiviral compounds
Disclosed are pharmaceutical compositions having an effective amount of substantially amorphous ledipasvir and an effective amount of substantially crystalline...
US-1,003,9778 Substituted-6,8-dioxabicyclo[3.2.1]octane-2,3-diol compounds as targeting agents of ASGPR
Compounds of Formula (A) are described herein and the uses thereof for the treatment of diseases, conditions and/or disorders mediated by pharmaceutical...
US-1,003,9777 Methods and pharmaceutical compositions of the treatment of autistic syndrome disorders
The present invention relates to a method for the treatment of an autistic syndrome disorder comprising administering to a subject in need thereof an effective...
US-1,003,9776 Hepato-protective beverage composition
The present invention relates to a hepato-protective beverage composition comprising a potable liquid, a primary hepato-protective agent comprising ...
US-1,003,9775 Preparation method for antitumor drug AP26113
Disclosed is a preparation method for an antitumor drug AP26113 (I). The method comprises the following preparation steps: cyclizing N-[2-methoxyl-4[4-(dimethyl...
US-1,003,9774 Neridronic acid for treating complex regional pain syndrome
Osteoclast inhibitors, such as neridronic acid, in an acid or a salt form can be used to treat or alleviate pain or related conditions, such as complex regional...
US-1,003,9773 Neridronic acid for treating arthritis
Oral dosage forms of osteoclast inhibitors, such as neridronic acid, in an acid or a salt form can be used to treat or alleviate pain or related conditions,...
US-1,003,9772 Methods and compositions for treating alcohol use disorders
Disclosed are methods and compositions for treating alcohol dependence by administration to a patient of an inhibitor of 11.beta.-hydroxysteroid dehydrogenases...
US-1,003,9771 Method for cancer cell reprogramming
In one embodiment, the invention provides a method of inhibiting cAMP efflux and increasing intracellular cAMP in a subject who suffers from, or who is at risk...
US-1,003,9770 Prostaglandin F2Alpha and analogues thereof for treating atrophic cutaneous scarring
A method of treating atrophic cutaneous scarring in humans is claimed. The method involves the topical application of a therapeutic amount of prostaglandin...
US-1,003,9769 Substituted triazolobenzodiazepines
This invention relates to novel substituted triazolobenzodiazepines of the Formula I: ##STR00001## wherein each of the variables are defined herein and...
US-1,003,9768 Axillary transdermal compound delivery system
A deodorant stick drug delivery system has one or more hydrophilic carriers, water, one or more gelling agents, an active ingredient, and a solvent. The active...
US-1,003,9767 Injection preparation and method for producing same
Provided are an injection preparation which include: an aqueous composition containing pemetrexed or a salt thereof, at least one antioxidant agent which is...
US-1,003,9766 Crystalline forms of (s)-4-amino-n-(1-(4-chlorophenyl)-3-hydroxypropyl)-1-(7h-pyrrolo[2,3-d] ...
The present invention discloses certain new solid state forms of (S)-4-amino-N-(1-(4-chlorophenyl)-3-hydroxypropyl)-1-(7H-pyrrolo[2,3-d]py- ...
US-1,003,9765 Vitamin supplement compositions with enhanced bioavailability
A vitamin supplement composition that includes a complex with enhanced bioavailability having a vitamin B complex, wherein the vitamin B complex includes: (a) a...
US-1,003,9764 Treatment and diagnosis of cancer and precancerous conditions using PDE10A inhibitors and methods to measure...
Disclosed are methods for treating cancer and precancerous conditions with PDE10A specific inhibitors and diagnosis of neoplastic diseases based on elevated...
US-1,003,9763 Pharmaceutical preparation comprising phenylalanine derivative
The disclosed pharmaceutical preparation comprises a compound represented by the chemical formula (A) or a pharmaceutically acceptable salt thereof, which is...
US-1,003,9762 Inhibitors of influenza viruses replication
Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample...
US-1,003,9761 Co-crystals and pharmaceutical compositions comprising the same
The present invention relates to compositions and co-crystals each comprising a compound of formula I having the structure: ##STR00001## wherein each of...
US-1,003,9760 Method of using diketopiperazines and composition containing them
The invention provides a method of inhibiting the effects of platelet activating factor (PAF). For instance, a disease or condition mediated by PAF...
US-1,003,9759 Quinolines as FGFR kinase modulators
The invention relates to new quinoline derivative compounds of formula (I), to pharmaceutical compositions comprising said compounds, to processes for the...
US-1,003,9758 Compositions and methods for inhibiting bacterial and viral pathogens
Compositions and methods including Amodiaquine (AQ) or N-Desethy Amodiaquine (DEAQ) are provided for treating, inhibiting, or preventing cathepsin B dependent...
US-1,003,9757 C-Met modulator pharmaceutical compositions
Pharmaceutical compositions and unit dosage forms comprising Compound I are disclosed. ##STR00001##
US-1,003,9756 Reducing memory loss in mammals suffering from alzheimer's disease
The disclosure relates to methods and compositions for reducing memory loss. Specifically, methods of using inhibitors of GAT-3 polypeptide activity to reduce...
US-1,003,9755 2-(azaindol-2-yl) benzimidazoles as PAD4 inhibitors
Compounds of formula (I) wherein; R.sub.1 is hydrogen or C.sub.1-6alkyl; R.sub.2 is hydrogen, C.sub.1-6alkyl, perhalomethylC.sub.0-5alkyl-O--, or ...
US-1,003,9754 Anti-viral compounds
Compounds effective in inhibiting replication of Hepatitis C virus ("HCV") are described. This invention also relates to processes of making such compounds,...
US-1,003,9753 Imidazo[4,5-c]quinoline and imidazo[4,5-c][1,5]naphthyridine derivatives as LRRK2 inhibitors
The present invention provides novel imidazo[4,5-c]quinoline and imidazo[4,5-c][1,5]naphthyridine derivatives of Formula (I), and the pharmaceutically...
US-1,003,9752 Methazolamide for the treatment of cancer
The present invention relates to methods of using methazolamide to treat pancreatic cancer. Pancreatic cancer can be treated by administering to a patient in...
US-1,003,9751 Reversing intestinal inflammation by inhibiting retinoic acid metabolism
An agent that increases local concentration of retinoic acid (RA) in the intestine through modifying enzymatic pathways involved in RA metabolism is...
US-1,003,9750 Solid forms of bendamustine hydrochloride
Novel solid forms of bendamustine hydrochloride are described, as well as methods of their preparation and use.
US-1,003,9749 Substituted pyrazole derivatives
A substituted pyrazole derivative includes a compound of the formula: ##STR00001## or a pharmaceutically acceptable salt thereof.
US-1,003,9748 PRMT1 inhibitors and uses thereof
Described herein are compounds of Formula (I-a) and (I-b), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the...
US-1,003,9747 Tetrahydrocyclopentapyrrole derivatives and a method for preparing the same
The present invention provides tetrahydrocyclopentapyrrole derivatives that can be used for preventing or treating peptic ulcer, gastritis or reflux...
US-1,003,9746 1-aryl-3-azabicyclo[3.1.0]hexanes: preparation and use to treat neuropsychiatric disorders
The invention provides novel, multiply-substituted 1-aryl-3-azabicyclo[3.1.0]hexanes, and related processes and intermediates for preparing these compounds, as...
US-1,003,9745 Enalapril formulations
Provided herein are stable enalapril oral liquid formulations. Also provided herein are methods of using enalapril oral liquid formulations for the treatment of...
US-1,003,9744 Post nerve injury rehabilitation effect-enhancing agent comprising alkyl ether derivative or salt thereof
Provided is a medicinal composition characterized by comprising an alkyl ether derivative represented by general formula [1] ##STR00001## [wherein: R.sup.1 and...
US-1,003,9743 Method of treating presbyopia using dithiol compounds and their derivatives
Dithiol compounds and derivatives thereof are disclosed. The agents are useful for treating ocular disease, especially presbyopia and cataract.
US-1,003,9742 Sn-2-monoacylglycerols and lipid malabsorption
The present invention relates generally to the field of lipids and in particular aims at improving lipid absorption, for example under conditions of lipid...
US-1,003,9741 Use of delta tocopherol for the treatment of lysosomal storage disorders
This disclosure relates generally to the treatment of lysosomal storage disorders. Specifically, the disclosure relates to a novel use of .delta. tocopherol in...
US-1,003,9740 Therapeutic combinations of sesquiterpenes and flavonoids
Provided is a pharmaceutical formulation and a method associated therewith for treating inflammation. The pharmaceutical formulation includes therapeutically...
US-1,003,9739 Nanoparticle isoflavone compositions and methods of making and using the same
The present invention is directed to formulations of genistein and methods for making and using the same. In particular embodiments, the formulations described...
US-1,003,9738 Ulcer treatment
The present invention relates to the treatment of peptic ulcers. In particular, the present invention provides methods and compositions for the treatment of...
US-1,003,9737 Multi-arm polymeric alkanoate conjugates
Among other aspects, provided herein are multi-armed polymer conjugates comprising an alkanoate-linker, compositions comprising such conjugates, and related...
US-1,003,9736 Method for transnasal delivery of blood-brain barrier permeation agent and therapeutic agent
Described herein is a method for treating a central nervous system disorder, said method comprising steps of first transnasally administering to or immediately...
US-1,003,9735 Treatment of diseases associated with hepatic stellate cell activation using ammonia-lowering therapies
Disclosed herein are methods of preventing, treating, and delaying the onset or progression of diseases associated with hepatic stellate cells (HSCs), such as...
US-1,003,9734 Eicosapentaenoic acid (EPA) formulations
Provided herein are compositions comprising eicosapentaenoic acid (EPA) and polar lipids (e.g., glycolipids and phospholipids), and which do not contain any...
US-1,003,9733 Compositions, method, and kits for treating pulmonary conditions
Compositions, methods, and kits useful for treating pulmonary conditions are provided herein. Such compositions can contain synergizing amounts of a...
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