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Patent # Description
US-1,004,1122 Biomarkers of mineralocorticoid receptor activation
The present invention relates to the use of Neutrophil Gelatinase-Associated Lipocalin (NGAL) and/or SERPINA3 as biomarkers of the Mineralocorticoid Receptor...
US-1,004,1121 Method for detection of a genetic variant
A method and kit for detecting a genetic variant associated with a disease or disorder, including incompatibility with a pharmaceutical. The method and kit...
US-1,004,1120 Predictive analysis for myocardial infarction
Compositions, systems and methods for the diagnosing the risk of acute myocardial infarction are provided. The methods described herein relate to the use of...
US-1,004,1119 Methods for the diagnosis of fetal abnormalities
The present invention relates to methods for detecting, enriching, and analyzing rare cells that are present in the blood, e.g. fetal cells. The invention...
US-1,004,1118 Method for analyzing water toxicity
A method for analyzing water toxicity, the method including: exposure experiment, sample collection, transcriptome detection, metabolome detection, screening of...
US-1,004,1117 Primers and methods for the detection and discrimination of nucleic acids
The present invention provides novel primers and methods for the detection of specific nucleic acid sequences. The primers and methods of the invention are...
US-1,004,1116 Methods and systems for processing polynucleotides
The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a...
US-1,004,1115 3'-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing
The present invention relates generally to 3'-OH unblocked nucleotides and nucleosides labeled and unlabeled with 5-methoxy-substituted nitrobenzyl-based...
US-1,004,1114 Targeted sequencing of biomolecules by pulling through a liquid-liquid interface with an atomic force microscope
A mechanism is provided for sequencing a biopolymer. The biopolymer is traversed from a first medium to a second medium. The biopolymer includes bases. As the...
US-1,004,1113 Apparatus, system, and method using immiscible-fluid-discrete-volumes
Various embodiments of the teachings relate to a system or method for sample preparation or analysis in biochemical or molecular biology procedures. The sample...
US-1,004,1112 Multiplexed, continuous-flow, droplet-based platform for high-throughput genetic detection
The present application relates to a continuous droplet flow microfluidic system, including a microfluidic chip including an optical detection section; a stage...
US-1,004,1111 Method for detecting and quantifying biomaterials by using activity of nucleic acid polymerase regulated by...
The present invention relates to a method of detecting and quantifying biomolecules using nucleic acid polymerase activity controlled by the target molecule,...
US-1,004,1110 Methods and apparatus for synthesizing nucleic acids
The invention provides improved methods for synthesizing polynucleotides, such as DNA and RNA, using enzymes and specially designed nucleotide analogs. Using...
US-1,004,1109 Method for detection of a nucleic acid target sequence
Disclosed is a method of facilitating detection of a nucleic acid target sequence. The method may include utilizing a toehold-mediated DNA strand displacement...
US-1,004,1108 Methods and compositions relating to optical super-resolution patterning
This disclosure provides methods for generating super-resolution patterns of molecules on substrates. In one aspect, disclosed herein is a method comprising...
US-1,004,1107 Methods and compositions for detection of small RNAs
Currently, the circularization of small RNAs is broadly regarded as an obstacle in ligation-related assays and explicitly avoided while short lengths of linear...
US-1,004,1106 Methods and compositions for isothermal whole genome amplification
Disclosed are methods and compositions for amplification of genetic material, including isothermal WGA of single cells.
US-1,004,1105 Methods and devices for detection of resistance to an enzyme inhibitor
Embodiments described herein relate to assay methods and kits for detecting resistance of any enzyme to its inhibitor due to functional alteration of the...
US-1,004,1104 Microfluidic device
A microfluidic device (1) comprises a substrate (10) transparent for imaging and having a plurality of spatially defined and separated cell channels (20) having...
US-1,004,1103 High throughput quantification and characterization of viruses and products thereof
The present invention provides a high throughput method to quantify and characterize the size and integrity of viruses and viral molecules using chromatographic...
US-1,004,1102 Expression of mammalian proteins in Pseudomonas fluorescens
The invention is a process for improved production of a recombinant mammalian protein by expression in a Pseudomonad, particularly in a Pseudomonas fluorescens...
US-1,004,1101 Compositions comprising a polypeptide having cellulolytic enhancing activity and a heterocyclic compound and...
The present invention relates to compositions comprising: a polypeptide having cellulolytic enhancing activity and a heterocyclic compound. The present...
US-1,004,1100 Method of producing sugar solution
A method of producing sugar solution by repeating a sugar solution production process includes steps (1) to (3), wherein a wash solution obtained in step (4) of...
US-1,004,1099 L-threonine and L-tryptophan producing bacteria strain and method of making same
The present invention relates to a microorganism able to produce L-threonine or L-tryptophan, and to a method for producing L-threonine or L-tryptophan by using...
US-1,004,1098 O-phosphoserine export protein and the method of producing O-phosphoserine using the same
The present invention relates to a novel isolated polypeptide having the ability to export O-phosphoserine (OPS) that is a precursor of L-cysteine, a vector...
US-1,004,1097 Deaeration process
A process for producing an oil, or a polyunsaturated fatty acid (PUFA), is described where an aqueous liquid comprising cells is deaerated, and the oil or PUFA...
US-1,004,1096 Methods and products for generating oils
Compositions and methods for enhancing secretion of oils from oil producing cells are described herein. In particular, secretion of oils is enhanced by treating...
US-1,004,1095 Process for producing a microbial storage compound
The invention relates to a process for producing a microbial storage compound, in particular polyhydroxyalkanoate, using micro-organisms capable of accumulating...
US-1,004,1094 Fermentation of glycerol to organic acids
The present invention is in the field of producing organic acids and other useful chemicals via biological fermentation using glycerol as a source of carbon....
US-1,004,1093 Semi-synthetic terephthalic acid via microorganisms that produce muconic acid
The invention provides a non-naturally occurring microbial organism having a muconate pathway having at least one exogenous nucleic acid encoding a muconate...
US-1,004,1092 Methods for genomic integration
Provided herein are methods of integrating one or more exogenous nucleic acids into one or more selected target sites of a host cell genome. In certain...
US-1,004,1091 Nucleic acid-containing lipid particles and related methods
Lipid particles containing a nucleic acid, devices and methods for making the lipid particles, and methods for using the lipid particles.
US-1,004,1090 Method of detecting and/or identifying adeno-associated virus (AAV) sequences and isolating novel sequences...
Adeno-associated virus rh.8 sequences, vectors containing same, and methods of use are provided.
US-1,004,1089 Resistance alleles in soybean
The present invention relates to methods and compositions for identifying, selecting and/or producing a soybean plant or germplasm having root knot nematode...
US-1,004,1088 Fungal resistant plants expressing CASAR
The present invention relates to a method of increasing resistance against fungal pathogens of the order Pucciniales, preferably the family Phacopsoraceae, in...
US-1,004,1087 Plants having increased tolerance to herbicides
The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said...
US-1,004,1086 Method for production of transgenic cotton plants
The present invention provides a method for producing transgenic Cotton plants. In one method transformed plants, that overexpress the transgene shows a...
US-1,004,1085 Plant type related protein, and coding gene and application thereof
A plant type related protein, and a coding gene and an application thereof are provided. The protein is: (a) a protein consisting of the amino acid sequence of...
US-1,004,1084 Nucleic acid encoding N-methylputrescine oxidase and uses thereof
The gene encoding N-methylputrescine oxidase (MPO) and constructs comprising such DNA are provided, including methods of regulating MPO expression independently...
US-1,004,1083 Regulatory nucleic acid molecules for enhancing seed-specific and/or seed-preferential gene expression in plants
The present invention is in the field of plant molecular biology and provides methods for production of high expressing seed-specific and/or seed-preferential...
US-1,004,1082 Regulatory nucleic acid molecules for enhancing seed-specific and/or seed-preferential gene expression in plants
The present invention is in the field of plant molecular biology and provides methods for production of high expressing seed-specific and/or seed-preferential...
US-1,004,1081 Regulatory nucleic acid molecules for enhancing seed-specific and/or seed-preferential gene expression in plants
The present invention is in the field of plant molecular biology and provides methods for production of high expressing seed-specific and/or seed-preferential...
US-1,004,1080 Modified promoter sequence and application thereof
The present invention relates to a modified plant promoter and applications using the same, including an expression construct comprising the promoter for...
US-1,004,1079 Compositions and methods for expressing genes in algae
The present application provides novel regulatory elements including promoter sequences from microorganisms. The application further discloses DNA constructs...
US-1,004,1077 DNA vectors, transposons and transposases for eukaryotic genome modification
The present invention provides polynucleotide vectors for high expression of heterologous genes. Some vectors further comprise novel transposons and...
US-1,004,1076 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
The invention provides immune regulatory oligonucleotides (IRO) as antagonist of TLRs and methods of use thereof. These IROs have unique sequences that inhibit...
US-1,004,1075 Modulation of pre-mRNA using splice modulating oligonucleotides as therapeutic agents in the treatment of disease
The present invention encompasses a class of compounds known as splice modulating oligonucleotides (SMOs) that modulate pre-mRNA splicing, thereby affecting...
US-1,004,1074 Euchromatic region targeting methods for modulating gene expression
Provided herein are oligonucleotides complementary to euchromatic regions of target genes that are useful for increasing expression of the target genes; related...
US-1,004,1073 Reduced size self-delivering RNAi compounds
The present invention relates to RNAi constructs with minimal double-stranded regions, and their use in gene silencing. RNAi constructs associated with the...
US-1,004,1072 Method for expression of small antiviral RNA molecules with reduced cytotoxicity within a cell
In one aspect, the invention provides methods and compositions for the expression of small RNA molecules within a cell using a retroviral vector (FIG. 1A)....
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