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Patent # Description
US-1,004,6014 Useful active agent for preventing and/or treating dandruff conditions of the scalp
The present invention relates to the cosmetic use of a lysate of a bacterium or bacteria belonging to the Vitreoscilla sp. genus (in particular the species:...
US-1,004,6013 Engineered bacteria for oral delivery of glucoregulatory proteins
Disclosed is an oral delivery system that overcomes major barriers encountered in the gastrointestinal tract, particularly rapid proteolytic degradation and low...
US-1,004,6012 Multipotent postnatal stem cells from human periodontal ligament and uses thereof
The invention generally relates to postnatal periodontal ligament stem cells and methods for their use. More specifically, the invention relates in one aspect...
US-1,004,6011 Compositions for inducing or suppressing an immune response
The present invention provides methods or kits with inflammatory cytokines to pretreat 1-ISCs to augment their immune modulatory effect, in prevention and...
US-1,004,6010 Methods of generating mesenchymal stem cells which secrete neurotrophic factors
A method of generating MSCs which secrete neurotrophic factors (NTFs) comprising incubating a population of undifferentiated mesenchymal stem cells (MSCs) in a...
US-1,004,6009 Method of treatment using a pharmaceutical composition comprising erythrocytes encapsulating a PLP-dependent...
The invention relates to a pharmaceutical composition containing a PLP-dependent enzyme and optionally its cofactor, pyridoxal phosphate (PLP), and/or a...
US-1,004,6008 Methods for treating chronic lymphocytic leukemia (CLL)
The present invention relates generally to the treatment of PML by infusion of activated and expanded autologous lymphocytes.
US-1,004,6007 Compositions and methods for treatment of short telomere disorders
The invention generally relates to methods of treating short telomere disorders using known compounds and pharmaceutical compositions comprising same. More...
US-1,004,6006 Compounds and methods for reducing the recruitment and/or migration of polymorphonuclear cells
Methods for reducing recruitment, migration, or both recruitment and migration of polymorphonuclear cells to a site of inflammation in an organ of a human...
US-1,004,6005 Composition and method of use for combinations of anti-viral protease, polymerase inhibitors and natural...
A composition and associated method for treating a hepatitis C virus (HCV) infection in a subject who is human being. The composition includes: an anti-viral...
US-1,004,6004 Methods and compositions for treatment of COPD diseases
The present disclosure relates to treatment of a pulmonary disease. The methods and kits provided herein facilitate relieving the symptoms resulting from the...
US-1,004,6003 Composition for treating neuropathy, a process and a method of treatment thereof
The present disclosure relates to a composition comprising eleutheroside-C, pinitol and sugars optionally along with pharmaceutically acceptable excipient or a...
US-1,004,6002 Method for treating cancer using chemokine antagonists
What is described is a method for treating cancer in a patient in need of such treatment through the use of an antagonist to CXCR1 and/or CXCR2 receptors by...
US-1,004,6001 Compositions and methods for reducing intraocular pressure
Compositions, kits, and methods for reducing intraocular pressure (IOP) in a subject (e.g., human) include at least one naturally occurring or synthesized...
US-1,004,6000 Use of 2-methylene-19-nor-(20S)-1.alpha.,25-Dihydroxyvitamin D.sub.3 to treat and prevent secondary...
Disclosed are methods of administering 2-methylene-19-nor-(20S)-1.alpha.,25-dihydroxyvitamin D.sub.3 to treat and/or prevent secondary hyperparathyroidism...
US-1,004,5999 Nutritional composition for the stimulation of muscle protein synthesis
The invention relates to the use of an anabolic amino acid derivative stimulus acting in combination with vitamin D for the manufacture of a medicament or...
US-1,004,5998 Solid form of abiraterone acetate
Combinations of (3.beta.)-17-(pyridin-3-yl)androsta-5,16-dien-3-yl acetate (Abiraterone acetate) with acidic substances such as citric acid, ascorbic acid,...
US-1,004,5997 Hypotensive lipid and timolol compositions and methods of using same
New compositions for and methods of treating ocular hypertension provide for effective treatment of ocular hypertension often using reduced concentrations of...
US-1,004,5996 Pharmaceutical composition for treatment of increased intraocular pressure
The invention provides novel pharmaceutical compositions for the treatment of increased intraocular pressure based on semifluorinated alkanes which are useful...
US-1,004,5995 Epidithiodioxopiperazine compound or its derivatives, and the use thereof
The present invention relates to an epidithiodioxopiperazine derivative represented by the following Chemical Formula 1 or its reduced derivative; a method for...
US-1,004,5994 Agents for treating multiple myeloma
The present invention relates to the use of compounds of a cannabinoid nature for inhibiting viability with increasing doses of myeloma cell lines. Furthermore,...
US-1,004,5993 Pharmaceutical preparation containing entecavir as active ingredient, and preparation method therefor
The present invention relates to a pharmaceutical preparation comprising entecavir as an active ingredient, wherein an antioxidizing agent is added to enhance...
US-1,004,5992 7-benzyl-4-(methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]- pyrimidin-5 (1h)-one, salts thereof...
This disclosure relates, at least in part, to a method of treatment. In one embodiment, the method of treatment comprises administering to a subject in need of...
US-1,004,5991 Methods of treating pediatric cancers
A method of treating a pediatric cancer in a subject in need thereof. The method includes administering to the subject a therapeutically effective amount of...
US-1,004,5990 ERBB4 inhibitors and methods of use thereof
Disclosed herein are methods of treating diseases that exhibit over-activation of the ERBB4 pathway, such as breast cancer and lung cancer. The method comprises...
US-1,004,5989 Quinazoline derivatives, compositions, and uses related thereto
The disclosure relates to quinazoline derivatives, compositions, and methods related thereto. In certain embodiments, the disclosure relates to inhibitors of...
US-1,004,5988 Spirocyclic compounds as tryptophan hydroxylase inhibitors
The present invention is directed to spirocyclic compounds which are inhibitors of tryptophan hydroxylase (TPH), particularly isoform 1 (TPH1), that are useful...
US-1,004,5987 Imidazoyl anilide derivatives and methods of use
The present invention provides kinase inhibitor analogs with improved properties, such as improved efficacy, pharmacokinetics, safety, and specificity. In some...
US-1,004,5986 Method, device, and system for radio resource management measurement
Embodiments provide a method for radio resource management measurement. The method includes: determining, by a UE according to a detected first reference...
US-1,004,5985 Heteroaryl compounds as BTK inhibitors and uses thereof
The present invention relates to pyrimidine compounds, and pharmaceutically acceptable compositions thereof, useful as BTK inhibitors.
US-1,004,5984 Combination therapy
The present invention provides a composition comprising zinc and trimethoprim, particularly in a weight ration of about 1:3 to about 1:7, as well as a...
US-1,004,5983 Heteroaryl pyridone and aza-pyrodine compounds
Heteroaryl pyridone and aza-pyridone compounds are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for...
US-1,004,5982 Substituted pyrido[2,3-b]pyrazines as FGFR kinase inhibitors
The invention relates to new pyridopyrazine derivative compounds of formula (I-A) or formula (I-B): ##STR00001## to pharmaceutical compositions comprising...
US-1,004,5981 Selective kinase inhibitors
The present disclosure relates to methods of modulating (for example, inhibiting) activity of JAK3, comprising contacting the JAK3 with a compound of Formula I...
US-1,004,5980 Inhibitor of p38 map kinase
A dry powder pharmaceutical formulation for inhalation including a compound of formula (I): ##STR00001## that is ...
US-1,004,5979 Anthelmintic compounds
The present invention relates to novel anthelmintic compounds of formula (I) below: ##STR00001## wherein Y and Z are independently a bicyclic carbocyclic or...
US-1,004,5978 Treatment of mastocytosis with masitinib
The treatment of mastocytosis, and in particular indolent forms of mastocytosis (including smoldering systemic, indolent systemic and cutaneous mastocytosis),...
US-1,004,5977 Use of nalmefene in non-alcoholic steatohepatitis
The present invention relates to new medical uses of morphinans such as nalmefene and naltrexone and their related derivatives, pharmaceutical formulations...
US-1,004,5976 Nicotine-containing liquid formulations and uses thereof
Nicotine liquid formulations and their use in therapy, for instance, in nicotine replacement therapy are described. More specifically, the technology relates to...
US-1,004,5975 Methods and ophthalmic devices used in the treatment of ocular allergies
Ophthalmic devices and methods of treating allergic conjunctivitis are disclosed herein.
US-1,004,5974 2-amino-6-(difluoromethyl)-5,5-difluoro-6-phenyl-3,4,5,6-tetrahydropyridin- es as BACE1 inhibitors
The present invention is directed to compounds of formula (I) which are inhibitors of the BACE1 enzyme. Separate aspects of the invention are directed to...
US-1,004,5973 Compositions and methods for treating nocturnal acid breakthrough and other related disorders
The present invention relates to, inter alia, pharmaceutical compositions comprising an acid labile proton pump inhibitor and a buffering agent and to use of...
US-1,004,5972 Hydroxypyridone derivatives, pharmaceutical compositions thereof, and their therapeutic use for treating...
Provided herein are hydroxypyridone derivatives, for example, a compound of Formula I, and pharmaceutical compositions thereof. Also provided herein are methods...
US-1,004,5971 Compositions for treating amyotrophic lateral sclerosis
The present invention relates to compositions and methods for the treatment of amyotrophic lateral sclerosis. More specifically, the present invention relates...
US-1,004,5970 Methods of use of cyclopamine analogs
The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula: ##STR00001##
US-1,004,5969 Isoxazoline-substituted benzamide compound and pesticide
A substituted alkenylbenzene compound of formula (4): ##STR00001## wherein X.sup.1 is selected from the group consisting of halogen atom, --SF.sub.5,...
US-1,004,5967 Thioureylene liquid compositions
The present invention relates to novel liquid compositions and formulations containing a thioureylene compound, a polysaccharide and a liquid vehicle. The...
US-1,004,5966 Compositions and methods for treating microbial infections
Embodiments of the presently-disclosed subject matter include activators of HssRS that induce endogenous heme biosynthesis by perturbing central metabolism....
US-1,004,5965 Transdermal formulation containing COX inhibitors
Disclosed are gel compositions suitable for the topical administration of an active compound having poor solubility and skin penetration, for example, of a...
US-1,004,5964 Polymorphic forms of ST-246 and methods of preparation
Polymorph forms of 4-trifluoromethyl-N-(3,3a,4,4a,5,5a,6,6a-octahydro-1,3-dioxo-4,6-ethenocy- cloprop[f]isoindol-2(1H)-yl)-benzamide are disclosed as well as...
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