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Patent # Description
US-1,005,2373 Protein and peptide-free synthetic vaccines against Streptococcus pneumoniae type 3
The present invention provides a protein- and peptide-free conjugate comprising a synthetic carbohydrate and a carrier molecule, wherein the synthetic...
US-1,005,2372 T cell expansion
A method of treating a cancer in a subject is disclosed, comprising: (1) isolating T cells from a subject; generating or expanding a population of T cells...
US-1,005,2371 Compositions and methods for treatment of cancer using bacteria
Provided herein are compositions comprising substantially non-viable Gram-negative bacterial organisms that have a substantial reduction in endotoxin activity...
US-1,005,2370 HER2/Neu cancer vaccine
Protein conjugate comprising a protein antigen for generating an immune response against the HER2/neu protein and an immunogenic carrier covalently bonded to...
US-1,005,2369 Aquaporin 2 protects cattle from ticks and tick-borne parasites
A novel method of using an aquaporin protein from Rhipicephalus microplus (RmAQP2), fragments of RmAQP2, and/or the cDNA encoding RmAQP2 and/or the fragments...
US-1,005,2368 Pegylated tissue kallikrein, and preparation method therefor and uses thereof
The present invention relates to polyethylene glycol (PEG) modified protein drugs, and a PEGylated tissue kallikrein, a preparation method and use thereof are...
US-1,005,2367 Compositions and methods for treating pathological calcification and ossification
The present invention includes compositions and methods for treating disease and disorders associated with pathological calcification or pathological...
US-1,005,2366 Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof
The present invention provides methods, compositions, and kits for the treatment of neurocutaneous syndromes, such as neurofibromatosis type I; disorders...
US-1,005,2365 Methods and products relating to GSK3.beta. regulation
The invention relates to methods and compositions for regulation of GSK3.beta. activity. The invention provides phosphorylated GSK3.beta. polypeptides and...
US-1,005,2364 Osteocalcin as a treatment for cognitive disorders
Methods and compositions for treating or preventing cognitive disorders in mammals, preferably humans, are provided. The methods generally involve modulation of...
US-1,005,2363 Mesenchymal stem cells for the treatment of CNS diseases
An isolated human cell is disclosed comprising at least one mesenchymal stem cell phenotype and secreting brain-derived neurotrophic factor (BDNF), wherein a...
US-1,005,2362 Glial cell line derived neurotrophic factor, obesity, and obesity-related diseases and conditions
The disclosure relates to therapeutic methods for regulating weight gain, metabolic syndrome, and insulin resistance. In certain embodiments, the disclosure...
US-1,005,2361 Liquid pharmaceutical composition of conjugated erythropoietin
A liquid pharmaceutical composition having a conjugated erythropoietin, buffer, sugar, tonicity modifier and amino acid as an aggregation inhibitor. The liquid...
US-1,005,2360 Methods for treating dermatomyositis or polymyositis by administering a soluble CTLA4 molecule
The present invention relates to compositions and methods for treating autoimmune diseases by administering to a subject a CTLA4 molecule that block endogenous...
US-1,005,2359 Composition for enhancing memory and learning function and/or cognitive function
Compositions, foods, and medicaments for enhancing memory and learning function and/or cognitive function are provided. Compositions, foods, and medicaments for...
US-1,005,2358 Composition comprising centipede grass extracts or fractions thereof as active ingredients
The present invention relates to a pharmaceutical composition for preventing or treating diabetes or dementia, comprising centipede grass (Eremochloa...
US-1,005,2357 Topical healing and scar treatment composition
Topical aqueous compositions are effective in minimizing scar formation and improving the visual appearance of scars. The compositions are also effective in...
US-1,005,2356 Topical medications for bruises and burns
Topical medications to treat the physical effects of bruises and burns. For bruises, the topical medication preferably includes therapeutically effective...
US-1,005,2355 Products and methods
The invention relates to fungal cells and spores, as well as extracts of either, for use, in particular, in prevention or treatment of Chlamydia, or...
US-1,005,2354 Anti-allergic composition
It is to provide a composition derived from lactic acid bacteria having an anti-allergic effect (an effect of suppressing allergic symptoms such as hay fever)...
US-1,005,2353 Human-derived bacteria that induce proliferation or accumulation of regulatory T cells
Species of human-derived bacteria belonging to the Clostridia class have been shown to induce accumulation of regulatory T cells (Treg cells) in the colon and...
US-1,005,2352 Therapeutic application of parenteral krill oil
A method of parenterally administering a composition, the method including parenterally administering to a person a composition including krill oil in an...
US-1,005,2351 Method for inducing angiogenesis
Disclosed herewith is a method for inducing angiogenesis using modified placental tissue or an extract thereof to treat conditions other than cardiovascular...
US-1,005,2350 Fabrication of gelatin hydrogel sheet for the transplantation of corneal endothelium
The invention provides a corneal endothelial composition comprising a transparent hydrogel scaffold and a single layer of cultured corneal endothelial cells on...
US-1,005,2349 Cell preparations for extemporaneous use, useful for healing and rejuvenation in vivo
The present invention relates to new plasma or new platelet-rich plasma preparations, new cell dissociation methods, new cell associations or compositions, a...
US-1,005,2348 Nitric oxide topical application apparatus and methods
A topical application of nitric oxide may be provided by two separate containers, each containing an active component media to produce nitric oxide when...
US-1,005,2347 Use of a block polymer comprising a block of poly(3-(methacryloylamino)propyltrimethylammonium chloride)...
The subject of the invention is use of block polymers with a block of poly(3-methacryloylpropyltrimethylammonium chloride) to direct neutralization of heparin,...
US-1,005,2346 Treatment of myelodysplastic syndromes with 2-O and,or 3-O desulfated heparinoids
Methods are presented for treating cancers and hematopoietic stem cell disorders, comprising administering to a subject with a cancer or hematopoietic stem cell...
US-1,005,2345 Assays, methods and kits for predicting renal disease and personalized treatment strategies
Assays, methods and kits for predicting a subject's (e.g., human) risk of primary glomerulopathy, secondary glomerulopathy or recurrence (e.g., post-transplant...
US-1,005,2344 Vitamin B.sub.12 nasal spray and method of use
The present invention relates generally to vitamin B.sub.12 nasal spray compositions and methods of using the same in the treatment of vitamin B.sub.12...
US-1,005,2343 Sterile formulation comprising a stable phosphorothioate oligonucleotide
The present invention relates to a composition comprising a phosphorothioate oligonucleotide and at least one fatty acid and/or at least one emulsifying agent,...
US-1,005,2342 Substituted nucleosides, nucleotides and analogs thereof
Disclosed herein are nucleosides, nucleotide analogs, methods of synthesizing nucleotide analogs and methods of treating diseases and/or conditions such as a...
US-1,005,2341 Method for preparing an anthelmintic composition, anthelmintic composition, veterinary treatment method and...
The present invention relates to an injectable anthelmintic composition of avermectin and basic albendazole sulfoxide for combatting parasites that infest...
US-1,005,2340 Use of ivermectin and derivatives thereof
The present invention relates to the new use of antiparasitic agents, such as ivermectin, abamectin/avermectin, doramectin and so on, and the design method of...
US-1,005,2339 Methods and compositions for treating symptoms of diseases related to imbalance of essential fatty acids
This invention relates to compositions containing combinations of a balanced phosphatidylcholine composition and one or more cannabinoids, a natural or...
US-1,005,2337 Compositions of obeticholic acid and methods of use
The disclosure relates to obeticholic acid formulations with improved stability, dissolution, and/or solubility, methods of preparing the same for use and...
US-1,005,2336 Pulmonary interstitial pneumonia treatment
Model and method of treating inflammatory diseases. Traditional treatments for such diseases include administering to the patient toxic anti-inflammatory drugs....
US-1,005,2335 Neuroprotection and myelin repair using Nestorone.RTM.
Methods for treating neurodegeneration and/or myelination in patients are disclosed comprising treating the patient with a progestin compound which exerts...
US-1,005,2334 Dosing regimen for sedation with CNS 7056 (remimazolam)
The invention relates to a dosing regimen for sedation with the fast-acting benzodiazepine CNS 7056 in combination with an opioid, in particular fentanyl,...
US-1,005,2333 Methods and systems for the delivery of a therapeutic agent
The present invention provides a liquid pharmaceutical composition comprising a therapeutic agent and an alkoxy-polyethylene glycol, for example,...
US-1,005,2332 Prostaglandin receptor EP2 antagonists, derivatives, compositions, and uses related thereto
The disclosure relates to Prostaglandin receptor EP2 antagonists, derivatives, compositions, and methods related thereto. In certain embodiments, the disclosure...
US-1,005,2331 3-(3H-imidazo[4,5-C]pyridin-2-yl)-1H-pyrazolo[3,4-C]pyridine and therapeutic uses thereof
Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an azaindazole...
US-1,005,2330 Substituted pyrido[3,4-b]pyrazines as Syk inhibitors
Provided are pyridopyrazine compounds of formula (I), pharmaceutical compositions thereof and methods of use therefore, wherein R.sup.1, R.sup.2, R.sup.3,...
US-1,005,2329 Viral prophylaxis treatment methods and pre-exposure prophylaxis kits
The present disclosure provides compositions and methods for the prevention of HSV infection in an HSV seronegative individual.
US-1,005,2328 Therapeutic composition to treat lesions caused by Herpes Simplex Virus
The present invention is generally directed toward therapeutic compositions for treating infections caused by Herpes Simplex Virus ("HSV"). The therapeutic...
US-1,005,2327 Method for treating liver diseases of various origins
The invention relates to medicine, in particular to gastroenterology, and lies in the field of treatment of liver diseases of various origins. For this purpose,...
US-1,005,2326 Antihepatotoxic agents
Antihepatotoxic agents include dihydropyrimidinone derivatives with 1,4-benzodioxane. The antihepatotoxic agents are compounds having the structural formula...
US-1,005,2325 Heat shock protein binding compounds, compositions, and methods for making and using same
The present subject matter relates to a compound represented by the general formula (I) or (I') or a pharmacologically acceptable salt thereof; pharmaceutical...
US-1,005,2324 Aldose reductase inhibitors and uses thereof
The present invention relates to novel compounds and pharmaceutical compositions thereof, and methods for promoting healthy aging of skin, the treatment of skin...
US-1,005,2323 Pharmaceutical compositions of 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-(trans)-4-methoxycyclohexyl)-3- ...
Provided herein are compositions of 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclohexyl)-- 3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one, solid...
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