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Patent # Description
US-1,005,2332 Prostaglandin receptor EP2 antagonists, derivatives, compositions, and uses related thereto
The disclosure relates to Prostaglandin receptor EP2 antagonists, derivatives, compositions, and methods related thereto. In certain embodiments, the disclosure...
US-1,005,2331 3-(3H-imidazo[4,5-C]pyridin-2-yl)-1H-pyrazolo[3,4-C]pyridine and therapeutic uses thereof
Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an azaindazole...
US-1,005,2330 Substituted pyrido[3,4-b]pyrazines as Syk inhibitors
Provided are pyridopyrazine compounds of formula (I), pharmaceutical compositions thereof and methods of use therefore, wherein R.sup.1, R.sup.2, R.sup.3,...
US-1,005,2329 Viral prophylaxis treatment methods and pre-exposure prophylaxis kits
The present disclosure provides compositions and methods for the prevention of HSV infection in an HSV seronegative individual.
US-1,005,2328 Therapeutic composition to treat lesions caused by Herpes Simplex Virus
The present invention is generally directed toward therapeutic compositions for treating infections caused by Herpes Simplex Virus ("HSV"). The therapeutic...
US-1,005,2327 Method for treating liver diseases of various origins
The invention relates to medicine, in particular to gastroenterology, and lies in the field of treatment of liver diseases of various origins. For this purpose,...
US-1,005,2326 Antihepatotoxic agents
Antihepatotoxic agents include dihydropyrimidinone derivatives with 1,4-benzodioxane. The antihepatotoxic agents are compounds having the structural formula...
US-1,005,2325 Heat shock protein binding compounds, compositions, and methods for making and using same
The present subject matter relates to a compound represented by the general formula (I) or (I') or a pharmacologically acceptable salt thereof; pharmaceutical...
US-1,005,2324 Aldose reductase inhibitors and uses thereof
The present invention relates to novel compounds and pharmaceutical compositions thereof, and methods for promoting healthy aging of skin, the treatment of skin...
US-1,005,2323 Pharmaceutical compositions of 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-(trans)-4-methoxycyclohexyl)-3- ...
Provided herein are compositions of 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclohexyl)-- 3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one, solid...
US-1,005,2322 Pharmaceutical formulations, processes, solid forms and methods of use relating to ...
Provided herein are formulations, processes, solid forms and methods of use relating to ...
US-1,005,2321 Nanoparticulate compositions and formulations of piperazine compounds
The present invention relates to storage stable nanoparticulate compositions of piperazine compounds. The pharmaceutical compositions comprising the...
US-1,005,2320 Substituted quinoxalines as FGFR kinase inhibitors
The invention relates to new quinoxaline derivative compounds of formula (I), ##STR00001## to pharmaceutical compositions comprising said compounds, to...
US-1,005,2319 Medicament for treating mental and behavioural disorders
The present invention relates to a medicament comprising lurasidone or a pharmaceutically acceptable acid addition salt thereof for treating pervasive...
US-1,005,2318 Glutamate agents in the treatment of mental disorders
Methods of treating mental disorders, including anxiety disorders such as obsessive-compulsive disorder, are provided. The methods comprise administering an...
US-1,005,2317 Method for treating or preventing hot flushes
The invention provides a neurokinin 3 receptor (NKR3) antagonist for use in the treatment, prevention or amelioration of hot flushes in a human subject, for...
US-1,005,2316 Methods and compositions for treatment of mitochondrial toxicity
The present invention relates to compositions and methods for prophylactic and/or therapeutic treatment of conditions related to mitochondrial function. In...
US-1,005,2315 Formulations of 2-(4-chlorophenyl)-N-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)m- ...
Provided herein are lyophilized formulations of 2-(4-chlorophenyl)-N-((2-(2,6 -dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide or a...
US-1,005,2314 Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer
Described herein are methods of treating non-metastatic castrate-resistant prostate cancer with anti-androgens.
US-1,005,2313 Compositions and methods for the treatment of presbyopia
The invention provides compositions and methods for the treatment of presbyopia. The compositions preferably comprise aceclidine and a polyol. The compositions...
US-1,005,2312 Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use
The present application relates to novel substituted imidazo[1,2-a]pyridine-3-carboxamides, to processes for their preparation, to their use alone or in...
US-1,005,2311 PPAR compounds for use in the treatment of fibrotic diseases
The invention relates to the use of a pan-PPAR agonist, or of a pharmaceutical composition containing said agonist, for the treatment of a fibrotic condition.
US-1,005,2310 Separase inhibitors and uses thereof
In some embodiments, the present disclosure pertains to compositions with compounds that inhibit Separase activity. In additional embodiments, the present...
US-1,005,2309 Bis-cyclic guanidine compound compositions, methods of use and treatment thereof
The present disclosure provides compositions including a bis-cyclic guanidine compound, pharmaceutical compositions including a bis-cyclic guanidine compound,...
US-1,005,2308 Spiro-lactam NMDA receptor modulators and uses thereof
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of...
US-1,005,2307 Micellar nanocomplex
The present invention relates to micellar nanocomplexes and a method of forming the same. The micellar nanocomplex comprises a micelle and an agent encapsulated...
US-1,005,2306 Selective octahydro-cyclopenta[C] pyrrole negative modulators of NR2B
Compounds that selectively negatively modulate NMDA receptors containing an NR1/NR2B subunit, pharmaceutical compositions comprising the compounds, and methods...
US-1,005,2305 Lipoic acid and derivatives thereof for the treatment of cystinuria
In various embodiments methods and composition are provided for the treatment and/or prophylaxis of cystinuria. In certain embodiments the methods involve...
US-1,005,2304 Compositions and methods for cancer therapy
The invention provides compositions and methods to treat a hyperproliferative disorder with ascorbate or a pharmaceutically acceptable salt thereof, at least...
US-1,005,2303 Cannabinoid formulations
The present invention provides stable, fast-acting liposomal and micelle formulations of cannabinoids that are suitable for pharmaceutical and nutraceutical...
US-1,005,2302 Green synthesis of reduced graphene oxide silica nanocomposite using nigella sativa seeds extract
The green synthesis of a reduced graphene oxide (rGO) silica (SiO.sub.2) nanocomposite using Nigella sativa seed extract includes mixing a quantity of carbon...
US-1,005,2301 Derivatives of propane diyl dicinnamate
The present invention provides a method for treating a cancer in a subject involving administering to the subject a compound of formula (II) or (II'): ...
US-1,005,2300 Methods and composition for suppression of deep seated fungal growth on skin
The present disclosure relates to methods and compositions for suppressing the growth of fungus on selected areas of the skin. A composition for suppressing...
US-1,005,2299 Alleviating oxidative stress disorders with PUFA derivatives
Some aspects of the invention provide for essential fatty acids which are substituted in specific positions to slow down oxidative damage by Reactive Oxygen...
US-1,005,2298 Rapid-acting, blood-arginine-level-increasable oral preparation comprising citrulline and arginine
The invention provides a method of increasing blood flow in a subject in need of increased blood flow by administering citrulline or a salt thereof and arginine...
US-1,005,2297 L-serine to be used as a drug for preventing and/or treating an inflammatory response of the skin
The invention relates to the use of L-serine as a drug for preventing and/or treating an inflammatory response of the skin caused by the overexpression and/or...
US-1,005,2296 Formulations for treating pain
Formulations, methods of manufacturing, methods of stabilizing, kits, and uses as medicament are provided, for example for the treatment of pain. The...
US-1,005,2295 Method, composition and package for bowel cleansing
The present invention provides a highly palatable colon cleansing formulation that utilizes a low chloride electrolyte-replenishing base solution. When...
US-1,005,2294 Processes for the preparation of 2,5-dihydroxybenzenesulfonic acid salts
Processes for the preparation of 2,5-dihydroxybenzenesulfonic acid salts of formula (I) and a crystalline form of potassium 2,5-dihydroxybenzenesulfonic acid...
US-1,005,2293 Curcumin infused milk beverage and a process for the preparation thereof
A Curcumin infused milk beverage composition comprising 0.05% to 0.15% alkalized Curcumin, standardized milk with fat, sugar and stabilizing agents, wherein the...
US-1,005,2292 Systems and methods for feeding sugar alcohol to ruminants during periods of heat stress
Systems and methods provide sugar alcohol to heat stressed ruminants to improve performance. During periods of high temperature or humidity, heat stressed...
US-1,005,2291 Compositions comprising electrohydrodynamically obtained fibres for administration of specific doses of an...
The present invention relates to electrospun fibers comprising i) a hydrophilic polymer that is soluble in a first solvent, ii) a bioadhesive substance that is...
US-1,005,2290 Enteric-coated hemoglobin multiparticulate for oral delivery of hemoglobin based oxygen carriers
The present invention provides an enteric-coated hemoglobin multiparticulate comprising a core, a hemoglobin formulation coating, an inner or sub-coating, and...
US-1,005,2289 Composition comprising an active agent with low aqueous solubility
The present invention relates to a composition comprising at least one active ingredient with low aqueous solubility, said active ingredient being present...
US-1,005,2288 Formulations for oral delivery of adsorbents in the gut
The invention relates to a formulation for the delayed and controlled delivery of an adsorbent into the lower intestine of mammals. The formulation includes a...
US-1,005,2287 Delivery system comprising a core and a digestible polymer shell
A delivery vehicle comprising a core (1) surrounded by a digestible polymer shell (4) having a melting and/or softening point above the body temperature of an...
US-1,005,2286 Controlled release and taste masking oral pharmaceutical composition
Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure...
US-1,005,2285 Apparatus and method for cryogranulating a pharmaceutical composition
Cryogranulation systems with improved dispenser assemblies are provided for use in manufacturing frozen pellets of pharmaceutical substances in a fluid medium....
US-1,005,2284 Lipid formulations for delivery of messenger RNA
The present invention provides, among other things, methods of delivering mRNA in vivo, including administering to a subject in need of delivery a composition...
US-1,005,2283 Composition for forming pluronic-based hydrogel with improved stability
Disclosed is a composition for forming an injectable hydrogel. The composition includes 1% by weight or less of a graphene-based material and 5% by weight or...
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