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Patent # Description
US-1,005,3737 Methods and compositions for treating cancer by identifying one or more ERK mutations
The invention is directed to methods, reagents, and kits for the detection of MAPK/ERK pathway mutations in a patient diagnosed for cancer. In one embodiment,...
US-1,005,3736 Methods and systems for identifying disease-induced mutations
The invention includes methods and systems for identifying diseased-induced mutations by producing multi-dimensional reference sequence constructs that account...
US-1,005,3735 Markers for the prediction of outcome of anthracycline treatment
The present invention relates to methods for predicting the outcome of anthracycline treatment of cell proliferative disorder patients. This is achieved by...
US-1,005,3734 Methods for treating, diagnosing, and monitoring lupus
Methods of identifying, diagnosing, and prognosing lupus, including certain subphenotypes of lupus, are provided, as well as methods of treating lupus,...
US-1,005,3733 Marker genes for oocyte competence
Cumulus cell (CC) gene expression is being explored as an additional method to morphological scoring to choose the embryo with the highest chance to pregnancy....
US-1,005,3732 Probe or probe set for evaluating influence of ultraviolet ray on skin and nucleic acid microarray
A probe or a probe set for evaluating influence of ultraviolet ray on the skin, which includes nucleic acids of (a), (b) or (c): (a) Nucleic acids including a...
US-1,005,3731 Sieve valves, microfluidic circuits, microfluidic devices, kits, and methods for isolating an analyte
The invention generally provides a sieve valve including: a substrate defining a channel; a flexible membrane adapted and configured for deployment at an...
US-1,005,3730 Independently removable nucleic acid sequencing system and method
A technique for sequencing nucleic acids in an automated or semi-automated manner is disclosed. Sample arrays of a multitude of nucleic acid sites are processed...
US-1,005,3729 Rapid aneuploidy detection
The present disclosure relates to methods for testing a human for aneuploidy. In some aspects, a plurality of chromosomal sequences in a DNA sample from a human...
US-1,005,3728 High density self-contained biological analysis
Devices, containers, and methods are provided for performing biological analysis in a closed environment. Illustrative biological analyzes include high density...
US-1,005,3727 Oligonucleotide and method for detecting target DNA in a sample by fluorescence from copper nanoparticles
The invention provides an oligonucleotide comprising a nucleotide sequence consisting of SEQ ID NO: 1. The invention also provides method for detecting target...
US-1,005,3726 Multiple amplification cycle detection
Methods and devices are provided for simultaneously amplifying a plurality of sample wells for a predetermined amount of amplification, detecting whether...
US-1,005,3725 In situ interaction determination
Methods, reagents, compositions, and kits for in situ interaction determination (ISID) via interaction-dependent polymerase chain reaction (ID-PCR) are provided...
US-1,005,3724 Methylation detection of the MGMT promoter
A real-time method of detecting the presence and/or amount of a methylated or unmethylated gene of interest in a DNA-containing sample, comprises the steps of:...
US-1,005,3723 Capsule array devices and methods of use
This disclosure provides microwell capsule array devices. The microwell capsule array devices are generally capable of performing one or more sample preparation...
US-1,005,3722 Enrichment and isolation of microbial cells and microbial nucleic acids from a biological sample
A method for enrichment and isolation of microbial cells and microbial nucleic acids from a biological sample is described. The method comprises (i) adding to...
US-1,005,3721 Antimicrobial resistance status determination device and method
A device and method for determining antimicrobial resistance status of a microorganism from a positive sample bottle is provided. The device may include a...
US-1,005,3720 Vectors and host cells comprising a modified SV40 promoter for protein expression
The present disclosure is directed to expression vectors, comprising a weakened SV40 promoter, and recombinant mammalian cells capable of producing high levels...
US-1,005,3719 Compositions and methods for synthesis of high fidelity oligonucleotides
Aspects of the invention relate to methods, compositions for synthesizing high fidelity oligonucleotides.
US-1,005,3718 Isolated bacterial strain of gluconacetobacter oboediens and an optimized economic process for microbial...
The present invention provides a novel and potent cellulose producing bacterial species, Gluconacetobacter oboediens which was isolated from mixed fruit residue...
US-1,005,3717 Biosynthesis of forskolin and related compounds
The invention described materials and methods for producing oxidized 13R-MO, such as forskolin. In particular, the invention describes P450s involved in...
US-1,005,3716 4-amino cinnamic acid production method using enzyme
This 4-amino cinnamic acid production method using the enzyme ammonia lyase can efficiently convert 4-amino phenylalanine into 4-amino cinnamic acid. This...
US-1,005,3715 Tailored oils
Recombinant DNA techniques are used to produce oleaginous recombinant cells that produce triglyceride oils having desired fatty acid profiles and regiospecific...
US-1,005,3714 Acid-tolerant yeast cell, method of producing organic acid using the same, and method of producing the yeast cell
Provided is an acid-tolerant yeast cell, a method of producing an organic acid by using the yeast cell, and a method of producing the yeast cell resistant to acid.
US-1,005,3713 Biological alkane oxidation
The invention relates to a method for oxidizing an alkane, comprising contacting the alkane with a type alkB oxidoreductase and using a type alkB oxidoreductase...
US-1,005,3712 Use of enzymes which catalyze pyruvate synthesis from formate and acetyl-CoA and bacteria expressing same
An isolated microorganism is disclosed being genetically modified to express pyruvate formate lyase (PFL) or 2-ketobutyrate formate lyase, wherein acetyl-CoA of...
US-1,005,3711 Method improving producer gas fermentation
Providing a microbial catalyst in a reaction broth, providing an adsorptive solid into the reaction broth, providing a producer gas into the reaction broth, and...
US-1,005,3710 Method for increasing ethanol yield from grain
A process for increasing ethanol yield from grain that includes mixing grain, water and cavitated enzymes to form a grain-based liquid medium wherein the...
US-1,005,3709 Insulator to improve gene transfer vectors
The present invention solves the problem of providing more efficient barrier insulators to avoid vector silencing and to increase expression in the setting of...
US-1,005,3708 TCR(alpha)-LCR-derived gene regulatory cassettes
A method of delivering a transgene to a cell is provided. The method uses a vector that contains a T-cell receptor alpha locus control region (TCR.alpha.LCR)...
US-1,005,3707 Pesticidal genes and methods of use
Compositions having pesticidal activity and methods for their use are provided. Compositions include isolated and recombinant polypeptides having pesticidal...
US-1,005,3706 Parental RNAi suppression of chromatin remodeling genes to control coleopteran pests
This disclosure concerns nucleic acid molecules and methods of use thereof for control of hemipteran pests through RNA interference-mediated inhibition of...
US-1,005,3705 Resistance alleles in soybean
The present invention relates to methods and compositions for identifying, selecting and/or producing a soybean plant or germplasm having brown stem rot (BSR)...
US-1,005,3704 Soybean plant and seed corresponding to transgenic event MON87712 and methods for detection thereof
The present invention provides a transgenic soybean comprising event MON87712 that exhibits increased yield. The invention also provides cells, plant parts,...
US-1,005,3703 Heterologous production of patchoulol, .beta.-santalene, and sclareol in moss cells
The present invention relates to methods for preparing patchoulol, .beta.-santalene, and sclareol in transgenic moss cells that include heterologous nucleic...
US-1,005,3702 Plastidic carbonic anhydrase genes for oil augmentation in seeds with increased DGAT expression
Recombinant DNA constructs comprise plastidic carbonic anhydrase coding sequences operably linked to polynucleotides encoding DGAT or transcription factors such...
US-1,005,3701 Protein having glycoalkaloid biosynthetic enzyme activity and gene encoding the same
Provided is DNA of biosynthetic enzyme of glycoalkaloid of solanaceous plant (Solanaceae) such as potato. Provided are a protein having activity on a...
US-1,005,3700 Soybean variety 01064288
The invention relates to the soybean variety designated 01064288. Provided by the invention are the seeds, plants and derivatives of the soybean variety...
US-1,005,3699 Soybean variety 01068892
The invention relates to the soybean variety designated 01068892. Provided by the invention are the seeds, plants and derivatives of the soybean variety...
US-1,005,3698 Recombinant microorganisms of Escherichia with L-threonine productivity and method of producing L-threonine...
The present invention relates to an E. coli mutant strain having enhanced L-threonine productivity, which is obtained by introducing the permease of...
US-1,005,3697 Programmable alternative splicing devices and uses thereof
Provided herein, among other things, is an RNA that comprises a first exon, a second exon, a third exon and a fourth exon, wherein the RNA is capable of being...
US-1,005,3696 MiRNA-489 in treatment of breast cancer
Breast cancer treatment methods and materials incorporating microRNA-489 are described. The methods and materials have been developed from identification of a...
US-1,005,3695 Modulation of CCR10 signals for treatment of skin and intestinal inflammatory diseases and infection
The invention provides compositions and methods for targeting CCR10 and/or the CCR10/ligand axis to modulate the immune response in a subject.
US-1,005,3694 Polycomb-associated non-coding RNAS
This invention relates to long non-coding RNAs (lncRNAs), libraries of those ncRNAs that bind chromatin modifiers, such as Polycomb Repressive Complex 2,...
US-1,005,3693 Method for controlling obesity using minimally invasive means
Methods for controlling obesity using minimally-invasive procedures including introducing embolic crystal particles that are naturally occurring and mostly...
US-1,005,3692 Methods relating to circulating tumor cell clusters and the treatment of cancer
Described herein are methods and assays relating to the presence and/or level of circulating tumor cells (CTCs). These CTC-Cs represent a highly metastatic...
US-1,005,3691 Treatment of NANOG related diseases by inhibition of natural antisense transcript to NANOG
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of NANOG, in particular, by targeting natural...
US-1,005,3690 Anti-miR-27b and anti-miR-148a oligonucleotides as therapeutic tools for treating dyslipidemias and...
The present invention relates to anti-miR-27b and anti-miR-148a oligonucleotides that are capable of decreasing the level and/or activity of miR-27b and...
US-1,005,3689 Methods for increasing efficacy of lipid formulated siRNA
This invention relates to methods for increasing the efficiency of siRNA administrations via pre-administration of an agent that lowers LDL receptor levels.
US-1,005,3688 De novo synthesized nucleic acid libraries
Disclosed herein are methods for the generation of nucleic acid libraries encoding for gRNA sequences. The gRNAs encoded by methods described herein may be...
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