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Patent # Description
US-1,005,8633 Biodegradable scaffolds
In some embodiments, the present invention provides compositions that comprise: (1) a biodegradable polymer matrix; and (2) at least one biodegradable...
US-1,005,8632 Nanoparticle-containing placental constructs and methods of use
A placental construct is provided. The placental construct includes a therapeutically effective amount of human birth tissue material and a nanoparticle...
US-1,005,8631 Tonsillectomy sponge
Described are methods of performing a surgical tonsillectomy, medical devices for treating a void created by removing tonsil tissue from a patient, surgical...
US-1,005,8630 Methods for inhibiting stenosis, obstruction, or calcification of a stented heart valve or bioprosthesis
Methods for inhibiting stenosis, obstruction and/or calcification of a heart valve following implantation in a vessel having a wall are disclosed. In one aspect...
US-1,005,8629 Absorbent article with skin care agent composition immobilized in a lipid phase
An absorbent article chosen from the group of diapers, panty liners, sanitary napkins and incontinence guards includes a liquid-pervious first sheet intended to...
US-1,005,8628 Trash can with fragrant oil dispensary
The trash can with fragrant oil dispensary is a waste container that is configured for use with solid domestic waste. The trash can with fragrant oil dispensary...
US-1,005,8627 Digital aroma cassette cartridge and matrix dispersion system for remote controls
The present invention is directed to a digital aroma system that provides a scented air on demand to various devices in various forms and user held devices...
US-1,005,8626 Sterilization device and sterilization method using same
A sterilization system comprises a reaction container configured to receive a sterilization object and sterilize the object; means for supplying peracetic acid...
US-1,005,8624 Recombinant promoters and vectors for protein expression in liver and use thereof
Disclosed herein are recombinant viral vectors comprising a liver specific promotor in operable combination with a heterologous nucleic acid sequence encoding a...
US-1,005,8623 Compositions and methods for modulating UTRN expression
Aspects of the invention provide single stranded oligonucleotides for activating or enhancing expression of UTRN. Further aspects provide compositions and kits...
US-1,005,8622 PH-sensitive peptides and their nanoparticles for drug delivery
A new nanoscale carrier made by one or more pH-sensitive peptides is provided for delivery of a biologically active substance. The peptides are composed of...
US-1,005,8621 Combination therapy with anti-HLA-DR antibodies and kinase inhibitors in hematopoietic cancers
The present invention relates to combination therapy with drugs, such as Bruton's tyrosine kinase inhibitors or PI3K inhibitors, with antibodies or ADCs against...
US-1,005,8620 Dextran-peptide hybrid for efficient gene delivery
One or more embodiments of the present invention provide a novel composition for gene delivery are directed to a group of polysaccharide polymers, having one or...
US-1,005,8619 P97-polynucleotide conjugates
Provided are conjugates between p97 (melanotransferrin) and polynucleotides such as small interfering RNA (siRNA) molecules, and related compositions and...
US-1,005,8618 PAK1-blocking 1,2,3-triazolyl esters
The present invention relates to a PAK1 blocking compound having a much higher bioavailability and cell permeability than traditional herbal PAK1 blockers or...
US-1,005,8617 Composition for forming a film
Provided is a composition for forming a film, the composition not having completely dissolved hydroxypropyl methyl cellulose (HPMC), and enabling formation of...
US-1,005,8616 Pharmaceutical compositions to reduce complications of ocular steroid
The present invention relates to pharmaceutical compositions comprising a combination of a lipid cake mixture comprising one or more phospholipids, with or...
US-1,005,8615 Semifluorinated alkane compositions
The invention provides novel compositions comprising semifluorinated alkanes and at least one compound sensitive or prone to oxidation. The compositions can be...
US-1,005,8614 Pharmaceutical compositions comprising meloxicam
Disclosed herein are compositions comprising an NSAID such as meloxicam in combination with a cyclodextrin and/or a carbonate or a bicarbonate. These...
US-1,005,8613 Pyrrolobenzodiazepine antibody drug conjugates and methods of use
The invention provides antibody-drug conjugates comprising an antibody conjugated to a pyrrolobenzodiazepine drug moiety via a disulfide linker, ...
US-1,005,8612 Impaired energy processing disorders and mitochondrial deficiency
Some aspects of the invention provide for a method of treating Impaired Energy Processing Disorders and Mitochondrial Deficiencies using polyunsaturated fatty...
US-1,005,8611 Use of .alpha.-(8-quinolinyloxy) mono-substituted phthalocyanine zinc for treatment of psoriasis
The present invention relates to a use of alpha-(8-quinolinyloxy) mono-substituted phthalocyanine zinc for the treatment of psoriasis. The use is suitable for...
US-1,005,8610 Methods for treating cancer by administering humanized pan-HER antibody compositions
The invention relates to humanized recombinant antibodies targeting the EGFR family receptors EGFR, HER2 and HER3, compositions comprising at least one...
US-1,005,8609 Antigen binding proteins that bind PD-L1
There is disclosed compositions and methods relating to or derived from anti-PD-L1 antibodies. More specifically, there is disclosed fully human antibodies that...
US-1,005,8608 Compositions of vaccines and adjuvants and methods for the treatment of urinary tract infections
This invention describes novel adjuvant compositions and formulations with excellent stability at refrigerated and room temperatures and up to and about...
US-1,005,8607 Polyvalent pneumococcal polysaccharide-protein conjugate composition
Provided is an immunogenic composition comprising 15 different polysaccharide-protein conjugates. Each of the conjugates comprises a capsular polysaccharide...
US-1,005,8606 Hepatitis B therapeutic vaccines
A fusion protein for use as a hepatitis B therapeutic vaccine is disclosed. The fusion protein comprises: (a) an antigen-presenting cell (APC)-binding domain or...
US-1,005,8605 Vaccine combinations
Vaccine combinations which comprise at least two or more of the following antigens: DTap-HEV-HepB-HPV suitable for administration in humans. A number of...
US-1,005,8604 Soluble HIV-1 envelope glycoprotein trimers
The present application relates to novel HIV-1 envelope glycoproteins which may be utilized as an HIV-1 vaccine immunogens, antigens for crystallization and for...
US-1,005,8603 Vaccine
The disclosure provides immunogenic compositions comprising human picornavirus peptides derived from structural proteins of the virus, constructs comprising the...
US-1,005,8602 Construction of West Nile virus and dengue virus chimeras for use in a live virus vaccine to prevent disease...
The present invention relates to attenuated, immunogenic West Nile virus chimeras built on a dengue virus backbone for the production of immunogenic, live,...
US-1,005,8601 Attenuated Mannheimia haemolytica vaccines and methods of making and use
The present invention provides attenuated M. haemolitica strains that elicit an immune response in animal against M. haemolitica, compositions comprising said...
US-1,005,8600 Detoxified Escherichia coli immunogens
Detoxified variants of the pathogenic E. coli `AcfD precursor` (orf3526) have been identified that raise a substantially similar immune response in a subject as...
US-1,005,8599 Suppressor cell function inhibition following Listeria vaccine treatment
This invention provides methods and compositions for using a live attenuated Listeria for inhibiting cell-mediated suppression of anti-disease infiltrating T...
US-1,005,8598 Peptides and combination of peptides for use in immunotherapy against various cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
US-1,005,8597 Treating glaucoma, cardiovascular diseases, and renal diseases
This document provides methods and materials related to treating glaucoma, ocular hypertension, cardiovascular diseases, and renal diseases. For example, this...
US-1,005,8596 Composition for enzymatic debridement
Methods and compositions for the enzymatic debridement of wounds are provided. Methods for preparing enzymatic debridement compositions are also provided. In...
US-1,005,8595 Pharmaceutical compositions and methods for fabrication of solid masses comprising TNF-inhibiting antibodies
Embodiments of the invention provide shaped masses comprising one or more drugs such as proteins or polypeptides and methods for forming such shaped masses. One...
US-1,005,8594 Treatment of depression and PTSD
Depression and PTSD are treated by administration of hCG, or an hCG analog, or a prodrug or metabolite of hCG or an hCG analog, in an amount equivalent to a...
US-1,005,8593 Methods and compositions for oral administration of proteins
This invention provides compositions that include a protein and at least two protease inhibitors, method for treating diabetes mellitus, and methods for...
US-1,005,8592 Long-acting peptide analogs
Long-acting agonistic analogs for CLR/RAMP receptors are provided that have an extended half-live in vivo.
US-1,005,8591 Co-administration of a parvovirus and a cytokine for therapy of pancreatic cancer
The present invention relates to a combination of a parvovirus and a cytokine, preferably IFN.sub.y, for use in treating pancreatic cancer, in particular a...
US-1,005,8590 Methods of treating amyotrophic lateral sclerosis by HGF
The invention presents a therapeutic agent (and progress suppressant) for amyotrophic lateral sclerosis (ALS) containing HGF and/or HGF gene as active...
US-1,005,8589 Stable pharmaceutical composition of Etanercept in a phosphate citrate buffer with glycine as an...
The present invention relates to the stable pharmaceutical compositions comprising tumor necrosis factor receptor Fc fusion protein (TNFR:Fc). More...
US-1,005,8588 Inhibitors of BCL-2
A protease resistant polypeptide includes an amino acid sequence that has a sequence identity at least 80% homologous to about 10 to 80 consecutive amino acids...
US-1,005,8587 Peptide composition for cancer treatment by inhibiting TRPV6 calcium channel activity
The invention includes an isolated peptide comprising all or part of the amino acid sequence: EGKLSSNDTE GGLCKEFLHP SKVDLPR (SEQ ID NO: 1), wherein the peptide...
US-1,005,8586 Use of human small leucine zipper protein in adipocyte differentiation procedure
The present invention relates to a use of a human small leucine zipper protein in the adipocyte differentiation procedure. More specifically, sLZIP binds with...
US-1,005,8585 Compositions and methods for treating conditions related to ephrin signaling with cupredoxins and mutants thereof
The present invention relates to compositions and methods of use of cupredoxins, and variants, derivatives and structural equivalents of cupredoxins that...
US-1,005,8584 Methods of improving behavioral therapies
This disclosure provides methods of using compounds that act to increase oxytocin release, including certain melanocortin receptor agonists, for treating or...
US-1,005,8583 Herbal compositions for treating neurological diseases and improving memory impairment
The present invention relates to a composition for preventing or treating neurological diseases including an extract of Euphoria longan fruit, red sage and...
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