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Patent # Description
US-1,005,8582 Therapeutic molecules and deviates for CRC
The chemically synthesized compound Tricin 7-O-beta-D-glucopyranoside, native to the plant Deschampsia Antarctica and present in aqueous extracts of the plant...
US-1,005,8581 Use of PHY906 as treatment for inflammatory bowel disease and/or irritable bowel syndrome
The present invention includes a method of using PHY906 for treating a bowel disorder including inflammatory bowel disease and irritable bowel syndrome....
US-1,005,8580 Herbal composition PHY906 and its use in chemotherapy
This invention provides herbal compositions useful for increasing the therapeutic index of chemotherapeutic compounds. This invention also provides methods...
US-1,005,8579 Dietary supplements containing extracts of cinnamon and methods of using same to promote enhanced sirtuin, cell...
A dietary supplement composition is provided for enhancing the expression of a sirtuin gene or protein. An inventive supplement composition includes at least...
US-1,005,8578 Human-derived bacteria that induce proliferation or accumulation of regulatory T cells
Species of human-derived bacteria belonging to the Clostridia class have been shown to induce accumulation of regulatory T cells (Treg cells) in the colon and...
US-1,005,8577 Thermo-stable strains, products and methods thereof
The present disclosure relates to thermo-stable/heat stable strain(s) of micro-organisms, obtaining such thermo-stable strains and incorporating them into food...
US-1,005,8576 Compositions and methods comprising a defined microbiome and methods of use thereof
The invention features the use of a defined microbial consortia for the replacement of a gut microbiome associated with disease. In particular, the invention...
US-1,005,8575 Probiotic composition comprising the novel isolated bacterial strain of brevibacterium casei AP9
The present invention discloses a novel isolated bacterial strain exhibiting probiotic properties. More particularly, the invention discloses a probiotic...
US-1,005,8574 Compositions comprising bacterial strains
The invention provides compositions comprising bacterial strains for treating and preventing inflammatory and autoimmune diseases.
US-1,005,8573 Dosing regimens for the mobilization of hematopoietic stem cells
Described herein are compositions and methods useful for mobilizing populations of hematopoietic stem and progenitor cells within a subject, as well as for...
US-1,005,8572 Placenta-derived multipotent stem cells
This disclosure provides isolated cells and compositions comprising one or more isolated cell(s) as described herein. In one aspect, the isolated cell is a...
US-1,005,8571 Fibrosis-causing agent
A fibrosis-causing agent is highly effective in the fibrosis of tissues. The fibrosis-causing agent contains a fibrosis inducer and a fibrosis promoter. A...
US-1,005,8570 Use of arsenic compounds for treatment of pain and inflammation
The present invention relates to the use of arsenic compounds such as sodium meta arsenite (NaAsO.sub.2), arsenic trioxide (As.sub.2O.sub.3), and arsenic...
US-1,005,8569 Lanthanum carbonate compositions
The invention relates to stable oral pharmaceutical compositions comprising lanthanum carbonate compounds and pharmaceutically acceptable excipients. The...
US-1,005,8568 Toxin binding system
In some embodiments, a composition and/or method may include a toxin binding system formulated for safe and effective mixture into various feed rations which...
US-1,005,8567 Methods and compositions for selectively removing potassium ion from the gastrointestinal tract of a mammal
The present invention provides methods and compositions for the treatment of ion imbalances using core-shell composites and compositions comprising such...
US-1,005,8566 Sulfated polygulonic acid polysaccharide or pharmaceutical salt thereof, preparation method therefor and use...
A polygulonic acid sulfate or pharmaceutically acceptable salt thereof, preparation method therefor and use thereof in the preparation of tumor growth and/or...
US-1,005,8565 2-aminoethanol dihydrogen phosphate-based dietary supplement and synthesis process thereof
This invention discloses a process for creating an amino acid-based vitamin and mineral dietary supplement and muscle builder having therapeutic activities such...
US-1,005,8564 Methods of treating acne
A method of treating acne in a human in need thereof comprising administering systemically to said human a tetracycline compound in an amount that is effective...
US-1,005,8563 System and method for diagnosis and treatment
This invention relates to a low cost rapid response diagnostic system to determine cortisol levels in patients selected as potential candidates for GCR...
US-1,005,8562 Methods of treatment of diseases
The invention provides a method of inhibiting vascular hyperpermeability in an animal in need thereof. The method comprises administering a ...
US-1,005,8561 Methods and related compositions for reduction of fat and skin tightening
Compositions and methods useful in the reduction of localized fat deposits and tightening of loose skin in subjects in need thereof using pharmacologically...
US-1,005,8560 Preservative free bimatoprost and timolol solutions
The present invention is directed to preservative-free solutions of bimatoprost and timolol for lowering intraocular pressure and treatment of glaucoma.
US-1,005,8559 Treatment or prevention of an intestinal disease or disorder
Disclosed are methods of treating or preventing an intestinal disease or disorder comprising administering to a subject a modulator of leucine rich repeat...
US-1,005,8558 Pharmaceutical composition comprising N1-cyclic amine-N5-substituted biguanide derivatives as an ingredient for...
The present invention provides a novel use of N1-cyclic amine-N5-substituted biguanide derivatives for preparing a medicine for preventing or treating fibrosis....
US-1,005,8557 Methods for treating subjects with prader-willi syndrome or smith-magenis syndrome
Provided are immediate or prolonged administration of certain potassium ATP (K.sub.ATP) channel openers, optionally in combination with growth hormone, to a...
US-1,005,8556 Method of treatment of aggression
The invention comprises a method of treatment of aggression and similar behavioral syndromes, such as impulsivity and irritability, by a pharmaceutical agent...
US-1,005,8555 Combination therapy
The invention relates to pharmaceutical compositions comprising: (a) at least one angiotensin receptor blocker or a pharmaceutically acceptable salt thereof,...
US-1,005,8554 Sustained release small molecule drug formulation
An injectable depot formulation includes a biocompatible polymer, an organic solvent combined with the biocompatible polymer to form a viscous gel, and a small...
US-1,005,8553 Fused heterotricyclic organic coumpounds, pharmaceutical compositions, and medical uses thereof
The invention provides fused heterocyclic organic compounds such as dihydropyrazolopyridotriazinones, compositions containing such compounds, medical kits, and...
US-1,005,8552 Combination of creatine, an omega-3 fatty acid, and citicoline
In one aspect, the invention relates to compositions comprising at least one creatine or creatine analog, at least one omega-3 fatty acid, and citicoline...
US-1,005,8551 Imidazolidinedione derivatives
The invention provides a compound of formula (Ia), and pharmaceutically acceptable salts thereof. The invention also provides use of the compounds or salts as...
US-1,005,8550 Methods of treating heart failure
Methods of treating heart failure include administering to a subject having heart failure an effective amount of a triazole compound that is an agonist of the...
US-1,005,8549 Imidazo[1,2-.alpha.]pyridine derivatives as modulators of the 5-HT.sub.2A serotonin receptor useful for the...
rmidazo[1,2-.alpha.]pyridine derivatives of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the 5-HT.sub.2A serotonin...
US-1,005,8548 Abuse-proofed dosage form
The invention relates to a dosage form that is thermoformed without discoloration and is safeguarded from abuse, comprising at least one synthetic or natural...
US-1,005,8547 Naloxone single agent and multilayer tablets
The present invention relates to a solid oral pharmaceutical composition comprising naloxone, or a pharmaceutical acceptable salt thereof, as an active...
US-1,005,8546 Pharmaceutical compositions of (R)-1-(2,2-difluorobenzo[D][1,3]dioxo1-5-y1)-N-(1-(2,3-dihydroxypropy1)-6- ...
A pharmaceutical composition comprising Compound 1, (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6- ...
US-1,005,8545 Method of treating pulmonary arterial hypertension
Disclosed herein are compositions and methods for the treatment of pulmonary hypertension, including pulmonary arterial hypertension. The methods include...
US-1,005,8544 (S)-N-(3-(6-isopropoxypyridin-3-yl)-1H-indazol-5-yl)-1-(2-(4-(4-(1-methyl-- ...
The invention includes a granular composition comprising the active ingredient (S)--N-(3-(6-isopropoxypyridin-3-yl)-1H-indazol-5-yl)-1-(2-(4-(4-(1-methy- ...
US-1,005,8543 Treatment of familial exudative vitreoretinopathy through S1PR2 inhibition
Methods and compositions are provided for the treatment of familial exudative vitreoretinopathy (FEVR) and retinopathy of prematurity (ROP) through the...
US-1,005,8542 Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith
A method for treating a prokaryotic infection in an animal or human by administering a pharmaceutically acceptable composition, comprising administering a...
US-1,005,8541 Multisubstituted aromatic compounds as serine protease inhibitors
There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of kallikrein, which compounds include substituted pyrazolyl or...
US-1,005,8540 2-amino-5,5-difluoro-6-(fluoromethyl)-6-phenyl-3,4,5,6-tetrahydropyridines as BACE1 inhibitors
The present invention is directed to compounds of Formula (I) which are inhibitors of the BACE1 enzyme. Separate aspects of the invention are directed to...
US-1,005,8539 Pharmaceutical compositions containing a PDE4 inhibitor and a PI3 delta or dual PI3 delta-gamma kinase inhibitor
This present invention relates to a method of treating a autoimmune, respiratory and/or inflammatory disease or condition (e.g., psoriasis, rheumatoid...
US-1,005,8538 Compositions comprising substituted benzofuroquinolizine and .alpha..sub.2-adrenergic agonists
The present invention relates to compositions for facilitating absorption and distribution of .alpha..sub.2-adrenergic agonists, where said composition...
US-1,005,8536 Pharmaceutical composition containing mirabegron
To provide: (1) a modified release liquid (suspension) containing mirabegron, (2) a ready-to-suspend pharmaceutical composition containing mirabegron, and (3) a...
US-1,005,8535 Nuclear transport modulators and uses thereof
The present invention relates to compounds of formula I: ##STR00001## and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising the...
US-1,005,8534 Benzothiophene derivatives and compositions thereof as selective estrogen receptor degraders
The present invention relates to compounds of formula I: ##STR00001## in which n, m, X, Y.sub.1, R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are defined in...
US-1,005,8533 Pharmaceutical composition containing Ginkgolide B and Xa factor inhibitor, preparation method thereof and use...
A pharmaceutical composition containing ginkgolide B and an Xa factor inhibitor xaban, a preparation method and use of the pharmaceutical composition, wherein...
US-1,005,8532 Methods of preventing progression to type 2 diabetes mellitus
The present invention provides compositions and methods for delaying or preventing progression to type 2 diabetes mellitus in individuals with prediabetes and...
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