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Patent # Description
US-1,006,4939 Combination therapy using c-Met inhibitor and IGF-1R inhibitor for c-Met inhibitor resistant cancers
A method of preventing and/or treating a cancer, the method including co-administering a dual inhibitor of c-Met (hereinafter, `c-Met inhibitor`) and an IGF-1R...
US-1,006,4938 Localized immunosuppression of allografts for peripheral nerve repair
Embodiments described herein relate to restorative solutions for segmental peripheral nerve (PN) defects using allografted PNs for stimulating PN repair. More...
US-1,006,4937 Treatment of dermal fibrosis
The present invention relates to RSPO and LGR antagonists, and methods of using the RSPO and LGR antagonists for treating or preventing fibrotic diseases.
US-1,006,4936 Mixed allergen compositions and methods for using the same
Mixed allergen compositions of two or more different allergens are provided. In some instances, the mixed allergen compositions include: a nut allergen; an...
US-1,006,4935 Human cytomegalovirus RNA vaccines
The disclosure describes HCMV ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
US-1,006,4934 Combination PIV3/hMPV RNA vaccines
The disclosure relates to respiratory virus ribonucleic acid (RNA) vaccines and combination vaccines, as well as methods of using the vaccines and compositions...
US-1,006,4933 Recombinant rift valley fever (RVF) viruses and methods of use
Described herein are recombinant RVF viruses comprising deletions in one or more viral virulence genes, such as NSs and NSm. The recombinant RVF viruses,...
US-1,006,4932 Integration of meningococcal conjugate vaccination
The invention provides a method for immunizing a patient, comprising administering multiple conjugates meningococcal capsular saccharides, wherein each...
US-1,006,4931 Proteins comprising MRSA PBP2a and fragments thereof, nucleic acids encoding the same, and compositions and...
Nucleic acid molecules which encode an MRSA PBP2a protein or a fragment thereof which comprises at least 245 amino acid are disclosed. Compositions comprising...
US-1,006,4930 Immunogenic compositions and methods for pigeon fever
The disclosure provides for immunogenic compositions against Pigeon Fever, and methods for their use and preparation. The immunogenic compositions, in alternate...
US-1,006,4929 Peptides and combination of peptides for use in immunotherapy against breast cancer and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
US-1,006,4928 Peptides and combination of peptides for use in immunotherapy against CLL and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
US-1,006,4927 Allogeneic tumor cell vaccination
The present invention relates to cancer immunotherapy, specifically to allogeneic tumor cell vaccines. According to some embodiments, the invention provides...
US-1,006,4926 Peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other...
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
US-1,006,4925 Use of anti-CD47 agents to enhance immunization
Methods are provided for enhancing immunization strategies by manipulation, e.g. in vitro manipulation, of phagocytic antigen presenting cells. In the methods...
US-1,006,4924 Immunotherapy against several tumors of the blood, such as acute myeloid leukemia (AML)
The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the...
US-1,006,4923 Therapeutic cancer vaccines derived from a novel dendritic cell line
The invention is in the field of medical sciences. It provides means and methods for the treatment of cancer. More in particular, it provides cells and cell...
US-1,006,4922 Compositions and methods for immune tolerance induction
Methods and compositions to reduce immunogenicity of proteins are disclosed. Compositions comprising therapeutic proteins (such as Factor VIII or any other...
US-1,006,4921 Botulinum toxin treatments of neurological and neuropsychiatric disorders
Methods for preventing or treating neuropsychiatric disorder and/or a neurological disorder including a neurological disorder mediated by the thalamus....
US-1,006,4920 Method for controlled ovarian stimulation using FSH and hCG
A product comprising follicle stimulating hormone (FSH) and human chorionic gonadotropin (hCG) for the treatment of infertility.
US-1,006,4919 Therapeutic method of inducing mitochondrial biogenesis to treat skin and muscle pathologies
A method of inducing mitochondrial biogenesis in a mammal is provided. The method comprises the step of administering to the mammal an interleukin-15 or nucleic...
US-1,006,4918 Mesenchymal stem cell differentiation
The present invention provides for methods and compositions for treating or preventing arthritis and joint injury.
US-1,006,4917 Compositions for treating pathological calcification conditions, and methods using same
The present invention includes compositions and methods for treating diseases or disorders associated with pathological calcification or pathological...
US-1,006,4916 Treatment method for microbial infection
A treatment composition for treating or preventing bovine mastitis, the treatment composition characterized in that it includes at least two components which...
US-1,006,4915 Fusion protein comprising albumin and retinol-binding protein
There is provided a fusion protein comprising albumin and retinol-binding protein (RBP), which can be used for preventing or treating fibrotic diseases. The...
US-1,006,4914 Mitochondrial-derived peptide MOTS3 regulates metabolism and cell survival
MOTS3 is a novel polypeptide. Methods of treating diseases such as diabetes, obesity, fatty liver, and cancer using MOTS3 and pharmaceutical compositions...
US-1,006,4913 Immunotherapy against several tumors including gastrointestinal and gastric cancer
The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the...
US-1,006,4912 Optically-based stimulation of target cells and modifications thereto
Stimulation of target cells using light, e.g., in vivo or in vitro, is implemented using a variety of methods and devices. One example involves a vector for...
US-1,006,4911 Peptides for treating cancer
The present invention relates to peptides for inhibiting angiogenesis. The present invention also relates to methods of inhibiting angiogenesis and methods of...
US-1,006,4910 Combination therapy for ischemia
The invention provides a combination treatment for ischemia conditions in or otherwise affecting the CNS, such as stroke. The treatment invoices administration...
US-1,006,4909 Compositions and methods for chronic use of a weight-gaining compound
Provided herein is a method of binding growth hormone secretagogue receptors in one or more companion animals or livestock to stimulate hunger independent of...
US-1,006,4908 Method for preventing, improving or treating liver disease
The present invention provides a method for preventing, alleviating or treating a liver disease, comprising administering a composition comprising a Triticum...
US-1,006,4907 Process to improve feed efficiency and carcass characteristics of animals
This invention relates to a process to improve the feed efficiency and carcass characteristics of (1) animals that are not showing clinical signs of disease or...
US-1,006,4906 Method of preparing fermented crude extract having angiotensin converting enzyme inhibiting activity
This invention is related to a method of preparing a fermented crude extract having angiotensin converting enzyme inhibiting activity. The method comprises the...
US-1,006,4905 Pharmaceutical preparation
Pharmaceutical preparations include at least one component that enhances sexual response and at least one other compound that enhances sexual sensitivity and...
US-1,006,4904 Treatment of Clostridium difficile infection
Provided herein are compositions and methods for the treatment or prevention of pathogenic infections.
US-1,006,4903 Lactic acid bacterium, drug, food or drink, and feed which contain the lactic acid bacterium
The Lactobacillus paracasei MCC1849 (NITE BP-01633) strain, which has a high IL-12 production-promoting action, is used as an ingredient of a drug, food or...
US-1,006,4902 Strain of Bifidobacterium animalis ssp. animalis
The invention relates to a novel strain of Bifidobacterium animals ssp. animalis, which is able, inter alia, to improve the function of the enteric nervous...
US-1,006,4901 Compositions and methods
Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of...
US-1,006,4900 Methods of populating a gastrointestinal tract
Methods and compositions for populating the gastrointestinal tract of a subject are described. Methods include administering to a subject a therapeutic...
US-1,006,4899 Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them
In alternative embodiments, the invention provides compositions, e.g., formulations, used for gastric, gastrointestinal and/or colonic treatments or lavage,...
US-1,006,4898 Listeria-based adjuvants
This invention provides methods and compositions for using Listeria monocytogenes as an adjuvant for enhancing immune responses in a subject.
US-1,006,4897 Treating a bacterial skin infection with a whole, leech saliva extract
Methods are also provided for isolating and using a whole-saliva leech extract in the treatment of a bacterial skin infection. The methods can include feeding a...
US-1,006,4896 Spinal disc regenerative composition and method of manufacture and use
The present invention provides a novel way to replenish the disc using retooled disc compositions to repair degenerative discs. There is no better source of...
US-1,006,4895 Compositions and methods for treating a pathogenic metabolic condition of the gut microbiota and derived diseases
The invention relates to the use as a drug or medical nutritional product in humans to treat a pathological dysbiosis and/or to prevent or treat at least one...
US-1,006,4894 Cell preparations for extemporaneous use, useful for healing and rejuvenation in vivo
The present invention relates to new plasma or new platelet-rich plasma preparations, new cell dissociation methods, new cell associations or compositions, a...
US-1,006,4893 Immune effector cells pre-infected with oncolytic virus
Compositions and methods are provided for the treatment of cancer. An immune effector cell population is pre-infected with an oncolytic virus. The combined...
US-1,006,4892 Method for producing an osteoinductive calcium phosphate and products thus obtained
The invention relates to a method for producing an osteoinductive calcium phosphate material, the method comprising the steps of providing a sintered calcium...
US-1,006,4891 Assembly of micelle aggregates of surfactant micelles and silver nanoparticles and use as antibacterial agent
An assembly of micelle aggregates, wherein each aggregate comprises micelles of an anionic surfactant and nano-sized particles of metallic silver. A product...
US-1,006,4890 Amorphous calcium carbonate for the treatment of calcium malabsorption and metabolic bone disorders
Provided are methods for treating calcium malabsorption and conditions associated with calcium malabsorption, employing the administration of a composition...
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