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Patent # Description
US-1,006,6256 Detection of genome editing
Methods, compositions, and kits are provided for quantifying a number or frequency of double stranded breaks in the genome of a cell or in the genomes of a...
US-1,006,6255 Pretreatment method for bacterial identification and antimicrobial susceptibility testing of positive blood...
Provided is a blood culture treatment technology, including a novel treatment technology of performing pretreatment of a positive blood culture to effectively...
US-1,006,6254 Diagnosis of constipation by analysis of methane concentration
Disclosed are methods of diagnosing constipation and constipation-predominant irritable bowel syndrome by screening for the presence of abnormally high levels...
US-1,006,6253 Method of measuring blood component amount
Provided is a method for measuring a blood component amount that can sufficiently and properly correct the blood component amount by measuring an Hct value with...
US-1,006,6252 Compositions and methods for the biosynthesis of vanillin or vanillin beta-D glucoside
Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to have reduced levels or activity of one or more alcohol...
US-1,006,6251 Polypeptides having catalase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having catalase activity and polynucleotides encoding the polypeptides. The invention also relates to...
US-1,006,6250 Engineered imine reductases and methods for the reductive amination of ketone and amine compounds
The present disclosure provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells...
US-1,006,6249 Method for producing acetylated sphingoid base
Provided is a means for producing an acetylated sphingoid base using modified microorganism in the genus Starmerella, particularly Starmerella bombicola. A...
US-1,006,6248 Method of producing lipid by using .beta.-ketoacyl-ACP synthase
The present disclosure provides a gene encoding a protein having .beta.-ketoacyl-ACP synthase activity having at least 60% or more identity with the amino acid...
US-1,006,6247 Process for producing an organic product from a carbon-based matter feedstock using gasification followed by...
The invention relates to a process for producing a fuel, in particular a liquid fuel, or another organic product, from a carbon-based matter feedstock,...
US-1,006,6246 Yeast cells having NADP(H)-dependent reductive TCA pathway from pyruvate to succinate
Recombinant yeast cells contain a reductive TCA pathway from phosphoenolpyruvate or pyruvate to succinate. At least one metabolic step in the pathway includes a...
US-1,006,6245 Microbial production of 3-hydroxypropionic acid
A yeast cell having a reduced level of activity of NAD dependent glyceraldehyde-3-phosphate dehydrogenase (GAPDH) has at least one exogenous gene encoding NADP...
US-1,006,6244 Process for producing ethanol and fermenting organisms
Processes for producing ethanol comprise saccharifying cellulosic material with a cellulolytic enzyme composition and fermenting the saccharified cellulosic...
US-1,006,6243 Surfactant improved ethanol fermentation method
A surfactant-improved ethanol fermentation method comprises adding a nonionic surfactant as a protection agent of yeast cell into a fermentation culture medium,...
US-1,006,6242 Artificial nucleases comprising engineered cleavage half-domains
Disclosed herein are engineered cleavage half-domains; fusion polypeptides comprising these engineered cleavage half-domains; polynucleotides encoding the...
US-1,006,6241 Compositions and methods of delivering treatments for latent viral infections
The invention provides delivery methods and compositions for antiviral therapeutics. Methods and compositions are provided for targeted delivery of antiviral...
US-1,006,6240 Nucleic acid vectors and uses thereof
There are disclosed nucleic acid vectors for use in both gram positive and gram negative bacteria. In embodiments the vectors comprise a prokaryotic expression...
US-1,006,6239 Fungal resistant plants expressing RLK2
The present invention relates to a method of increasing resistance against fungal pathogens of the order Pucciniales, preferably the family Phacopsoraceae, in...
US-1,006,6238 Methods for producing antibodies
Methods for producing antibodies are provided and include transforming a plant cell with a nucleic acid encoding a heavy chain of an antibody, a light chain of...
US-1,006,6237 Polypeptides having beta-xylosidase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having beta-xylosidase activity and polynucleotides encoding the polypeptides. The invention also relates...
US-1,006,6236 Small interfering RNAs with target-specific seed sequences
Disclosed are methods for design and synthesis of siRNA libraries, siRNA libraries produced thereby, siRNA molecules, and uses thereof.
US-1,006,6235 Use of multiple transformation enhancer sequences to improve plant transformation efficiency
The present invention relates to methods and compositions for improving the efficiency of Agrobacterium- and Rhizobium-mediated plant cell transformation by use...
US-1,006,6234 Yeasts modified to use carbon dioxide
The invention relates to yeast cells modified to express a functional type I RuBisCO enzyme, and a class II phosphoribulokinase. The expression of these enzymes...
US-1,006,6233 Method of modulating cell resistance
The present invention relates to the use of one or more cas genes for modulating resistance in a cell against a target nucleic acid or a transcription product...
US-1,006,6232 E. coli separatome-based protein expression and purification platform
Provided is a separatome-based peptide, polypeptide, and protein expression and purification platform based on the juxtaposition of the binding properties of...
US-1,006,6231 Methods for improving recombinant protein expression
Materials and methods are provided which allowed for increased expression of a transfected gene of interest in a recombinant host cell.
US-1,006,6230 Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
The invention provides immune regulatory oligonucleotides (IRO) as antagonist of TLRs and methods of use thereof. These IROs have unique sequences that inhibit...
US-1,006,6229 Treatment using truncated Trk B and Trk C antagonists
Disclosed herein are methods, compositions, vectors, and kits comprising an antagonist of a truncated TrkC or a truncated TrkB. Also described herein are...
US-1,006,6228 Oligonucleotides for treating expanded repeat diseases
The invention provides for a method for selectively reducing the expression of a mutant mRNA and/or protein having an expanded nucleotide repeat relative to a...
US-1,006,6227 Mapping of genomic interactions
The present invention relates to genomic analysis. In particular, the present invention provides methods and compositions for mapping genomic interactions.
US-1,006,6226 RNA isolation from soluble urine fractions
The invention provides methods for isolating RNA from the soluble fraction of urine. The methods can be used for detecting the presence or absence of an RNA, or...
US-1,006,6225 Nitrile hydratase
Provided is an improved nitrile hydratase with improved catalytic activity. Also provided are DNA for coding the improved nitrile hydratase, a recombinant...
US-1,006,6224 Method for purifying and quantifying thrombin and its degradation polypeptides
Provided is a method for purifying .alpha.-thrombin and for quantifying .alpha.-thrombin and its degradation polypeptides in a liquid proteinatious solution....
US-1,006,6223 Nucleic acids useful for integrating into and gene expression in hyperthermophilic acidophilic Archaea
The present invention provides for a novel recombinant or isolated nucleic acid useful for integrating or being maintained in an Archaea or acidophilic...
US-1,006,6222 Amylases, nucleic acids encoding them and method of producing an oil
In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using...
US-1,006,6221 Methods for screening and using CRISPR/Cas9 guidance RNA sequence from HIV provirus genome
The invention pertains to compositions and methods for identifying gRNAs that are effective in treating a latent HIV infection. An embodiment of the invention...
US-1,006,6220 Polypeptides having organophosphorous hydrolase activity
The present invention relates to isolated polypeptides having organophosphorous hydrolase activity, and polynucleotides encoding the polypeptides. The invention...
US-1,006,6219 Thioesterases and their use
Disclosed are nucleotide sequences encoding thioesterase enzymes, methods for their production, their use in methods to form thioesters, and their use in...
US-1,006,6218 Nucleic acid modifying enzymes
This invention provides for an improved generation of novel nucleic acid modifying enzymes. The improvement is the fusion of a sequence-non-specific...
US-1,006,6217 Thermophilic organisms for conversion of lignocellulosic biomass to ethanol
Mutant thermophilic organisms that consume a variety of biomass derived substrates are disclosed herein. Strains of Thermoanaerobacterium saccharolyticum with...
US-1,006,6216 Bionanomaterials and their synthesis
The use of biomaterials, such as viruses and virus-like particles, to form nanostructures is generally disclosed. For instance, rod-like viruses can be used to...
US-1,006,6215 Hexon isolated from simian adenovirus serotype 19, hypervariable region thereof and chimeric adenovirus using...
Novel hexon isolated from simian adenovirus serotype 19 encoded in the polynucleotide defined as SEQ ID NO: 3, hepervariable region thereof, chimeric adenovirus...
US-1,006,6214 Compositions and methods for enhancing virus replication
Described herein is a method of enhancing virus replication in permissive cells that express a receptor to FGF2 protein. The method includes administering FGF2...
US-1,006,6213 Use of centrifugation-aided infection to increase virus titer
The invention relates to a process for increasing the observed titer of a virus stock for the purpose of increasing the calculated log reduction (LRV) in virus...
US-1,006,6212 Method for preparing induced pluripotent stem cells using synthetic peptide
Provided is a method of preparing induced pluripotent stem cells using a synthetic peptide, and more particularly, to a method of preparing induced pluripotent...
US-1,006,6211 Method for screening for pluripotent stem cell growth-promoting factor
This invention relates to a method for screening for a growth-promoting factor for pluripotent stem cells with a conditioned medium which is generated by...
US-1,006,6210 Differentiation of human embryonic stem cells into pancreatic endocrine cells
The present invention provides methods to promote differentiation of pancreatic endoderm cells to pancreatic endocrine rich clusters and to enhance insulin...
US-1,006,6209 Isolation and cultivation of stem/progenitor cells from the amniotic membrane of umbilical cord and uses of...
The present invention relates to the generation of a chondrocyte using mesenchymal stem/progenitor cells obtained from the amniotic membrane of umbilical cord...
US-1,006,6208 Kit and method for promoting mesenchymal stem cell differentiation
The present invention is related to a kit comprising: (a) a mesenchymal stem cell; (b) a gelatin-hyaluronan-chondroitin tri-copolymer scaffold; (c) a...
US-1,006,6207 Natural killer cells with enhanced immune response
The invention relates to a specialized subpopulation of natural killer cells that have enhanced effector functions and the potential to kill malignant tumor...
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