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Compounds for treating impaired fundic relaxation
The present invention concerns compounds of formula (I) a stereochemically isomeric form thereof, an N-oxide form thereof or a pharma-ceutically acceptable acid...
Adamantane derivatives and resin compositions using the same as raw
The adamantane derivatives of the present invention which are represented by the general formula (1): ##STR00001## wherein X is a hydrogen atom, alkyl,...
Charged compounds comprising a nucleic acid binding moiety and uses
Charged compounds are provided that comprise one or more regions of localized positive charge, compositions comprising such compounds, methods of synthesizing...
Quinuclidine derivatives and medicinal compositions containing the same
The invention provides 3(R)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicy- clo[2.2.2] octane in salt form, pharmaceutical compositions...
Aminothiol ester compounds, pharmaceutical and cosmetics compositions
containing same and uses thereof
The invention relates to novel aminothiol ester compounds having the general formula (I): ##STR00001## and to a method for preparing them and to their use in...
Hydrochloride salts of 5-[4-[2-(n-methyl-n-(2-pyridyl)
A substantially non-hydrated and non-hygroscopic or slightly hygroscopic hydrochloride salt of ...
Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1
The present invention relates to compounds with the formula (I) ##STR00001## and also to pharmaceutical compositions comprising the compounds, as well as to...
Vitamin D derivatives
The object of the present invention is to provide a vitamin D derivative exhibiting excellent physiological activity as medicines, in particular as therapeutic...
Medicine, carrier for medicine, method of producing medicine, and method
of tumor treatment
A medicinal preparation capable of lowering the threshold of cavitation and generating active oxygen species via acoustic cavitation caused by an ultrasound is...
Water stabilized medicinal aerosol formulation
This invention relates to a medicinal aerosol suspension formulation and more particularly, to a medicinal aerosol formulation containing a particulate drug or a...
Medicine feeding apparatus
An object of the invention is to provide a medicine feeding apparatus in which it is possible to prevent a medicine from being broken by well absorbing and...
.alpha.-Glucosidase inhibitors and their synthesis from a natural source
The present invention provides novel .alpha.-glucosidase inhibitory compound (-)-mesquitol and its analogs isolated in significant yield from traditional...
Antimicrobial prevention and treatment of human immunedeficience virus and
other infectious diseases
An improved medical treatment and medicine is provided to quickly and safely resolve HIV and other microbial infections. The inexpensive medicine can be self...
Respiratory syncytial virus replication inhibitors
The present invention concerns compounds of formula (I), prodrugs, N-oxides, addition salts, quaternary amines, metal complexes and stereochemically isomeric...
Protein and DNA thereof
The present invention relates to a novel protein belonging to an ADAM family, a partial peptide thereof or a salt thereof, a DNA encoding the protein, a...
Sugar-modified liposome and products comprising the liposome
The present invention provides a sugar-modified liposome having a sugar chain bonded to its membrane surface, preferably through a linker protein, and having...
Dispensing apparatus and method for liquid products, particularly
A dispensing apparatus for a liquid product, the apparatus comprising a) a housing (2) or frame (3), b) a receptacle (4) for the liquid with a feed nozzle (4a)...
The present invention provides a pharmaceutical preparation comprising a compound which can be obtained by reacting a compound having a free amino group with a...
Farnesyl transferase inhibiting 6-heterocyclylmethyl quinolinone
This invention comprises the novel compounds of formula (I) ##STR00001## wherein r, t, Y.sup.1--Y.sup.2, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and...
Preventive or therapeutic medicines for diabetes containing
fused-heterocyclic compounds or their salts
The present invention provides a preventive or therapeutic medicine for diabetes containing as an active ingredient a fused-heterocyclic compound of the formula...
Process for producing optically active oxoheptenoic acid ester
A novel process for producing an optically active (E)-7-[2-cyclopropyl-4-(4-fluorophenyl quinolin-3-yl]-5-hydroxy-3-oxohept-6-enoic acid ester of formula (III) ...
Imidazole compounds and medicinal use thereof
Imidazole compounds represented by general formula (I): ##STR00001## wherein each symbol is as defined in the specification, and salts thereof, and a...
To provide a swallowing-assistive drink for medicines that improves swallowing various medicines, is convenient and substitutable with ordinary drinking water,...
The present invention relates to heterocyclo alkylsulfonyl pyrazoles of the formula I: ##STR00001## wherein the ring of the formula ...
A method for treating a living body afflicted with a cancer selected from lung and ovarian carcinoma, comprising the step of administering to the living animal...
Benzimidazole anti-inflammatory compounds
The present invention relates to novel triazolo-pyridines of the formula I ##STR00001## wherein Het is an optionally substituted 5-membered heterocycle...
Glucopyranosyloxypyrazole derivatives, medicinal compositions containing
the same and intermediates in the...
The present invention relates to glucopyranosyloxypyrazole derivatives represented by the general formula: ##STR00001## wherein R.sup.1 represents a hydrogen...
Multi-purpose medicine organizer
Described is a preferred medicine organizer including both pill bottle and individual pill storage units. Preferred devices include upper and lower frame members...
Method of providing a therapeutic regimen and prefabricated container
An integrated medicament package comprises a prefabricated medicament container having a plurality of initially open top blisters, a closure cover affixed to one...
Monocyclic compounds and their use in medicine: process for their
preparation and pharmaceutical compositions...
The present invention relates to novel antiobesity and hypocholesterolemic compounds, their derivatives, their analogs, their tautomeric forms, their...
Breast cancer transcription factor gene and uses
The present invention relates to all facets of novel polynucleotides, the polypeptides they encode, antibodies and specific binding partners thereto, and their...
Farnesyl transferase inhibiting quinoline and quinazoline derivatives as
farnesyl transferase inhibitors
This invention comprises the novel compounds of formula (I) wherein r, s, t, Y.sup.1--Y.sup.2, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.7 have...
Triazole compounds as transforming growth factor (TGF) inhibitors
Novel triazole compounds, including derivatives thereof, to intermediates for their preparation, to pharmaceutical compositions containing them and to their...
Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions
containing the same and intermediates in the...
The present invention relates to glucopyranosyloxybenzylbenzene derivatives represented by the general formula: ##STR00001## wherein R.sup.1 represents a...
X-ray absorbing material and variants
The present invention relates to an X-ray absorbing material that can be used in medicine as well as in the manufacture of special protective clothing,...
Airway products having LEDs
The present invention relates to an illuminated airway product that will allow visualization of the airway of a patient during intubation. The illuminated airway...
Compounds of the general formula (I): ##STR00001## or a salt thereof, wherein R.sup.1 is hydrogen, hydroxyl or halogen; R.sup.2 is NHSO.sub.2CH.sub.3,...
Neuroprotective and retinoprotective ophthalmologic drugs
The invention concerns a neuroprotective and retinoprotective medicine, whereof the active principle is selected among a group of compounds consisting of...
Method of determining a chemotherapeutic regimen based on ERCC1 and TS
The present invention relates to prognostic methods which are useful in medicine, particularly cancer chemotherapy. The object of the invention to provide a...
Noninvasive medical instrument
A noninvasive medical instrument having a core and a flexible outer coil surrounding about the core to form an elongated body. The elongated body has a rounded...
A needleless syringe that provides the necessary high pressure, is easily generated despite the utilization of relatively thin-walled glass ampules for storing...
Wristband/label assembly business form and method
A business form particularly adapted for use during medical emergencies includes in a first embodiment a wristband/label assembly that is readily separable from...
Disposable shoe insert
A disposable shoe insert having a soft, durable, resilient, absorbent and "high coefficient of friction" surface in contact with the human foot is provided. The...
Radiation detection device for nuclear medicine diagnosis device and
detecting method therefor
In case of performing so-called "PET acquisition", a nuclear medical diagnosis apparatus according to the present invention does not set only gamma rays which...
Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions
containing the same and intermediates for...
The present invention relates to benzylphenol derivatives represented by the general formula: ##STR00001## wherein R.sup.11 represents a hydrogen atom or a...
Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-
-2,4-dione maleic acid salt
A hydrate of 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione- , maleic acid salt, characterized in that it: (i) comprises water in the ...
Polymorphous forms of rifaximin, processes for their production and use
thereof in medicinal preparations
Crystalline polymorphous forms of the rifaximin (INN) antibiotic named rifaximin .alpha. and rifaximin .beta., and a poorly crystalline form named rifaximin...
Mono- and diacylglycerol acyltransferases and methods of use thereof
Nucleic acid compositions encoding polypeptide products with diglyceride acyltransferase and/or monoacylglycerol acyltransferase activity, as well as the...
Substrate and method for growing shiitake mushrooms [Lentinus edodes
(Berk.) singer] and new shiitake strain
The present invention describes a new substrate comprising olive oil waste as the nutrient for growing edible and medicinal shiitake mushrooms (Lentinus edodes)...