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Allosteric adenosine receptor modulators
The present invention relates to compounds of formulas (IA), (IB), and (IC): ##STR1## the preparation thereof, pharmaceutical formulations thereof, and their...
Macro-porous composite support for medicinal substance(s) that can be used
as a bone reconstitution material...
The invention relates to a macro-porous composite that can be used as a bone reconstitution material. The composite is made up of a combination of synthetic...
Method of producing benzamide derivatives
In the case that a selectively monoacylated phenylenediamine derivative which is useful as any of medicines, agricultural chemicals, animal drugs and the...
Retinoic acid mimetic anlides
The present invention is concerned with compounds of formula ##STR1## the N-oxides, the pharmaceutically acceptable addition salts and the stereochemically...
Use of a compound with affinity for the mitochondrial benzodiazepine
receptor in cancer therapy
The present invention relates in particular to a combination product comprising at least one compound with affinity for the mitochondrial benzodiazepine...
Substituted dimeric compounds
The invention relates to compounds of formula (I): wherein: A represents NR.sup.1 C(Q)R.sup.2, C(Q)NR.sup.2 R.sup.3 or NR.sup.1 C(Q)NR.sup.2 R.sup.3, B represents...
Solid thermoformable controlled-release pharmaceutical composition
The present invention relates to a new solid controlled-release pharmaceutical composition obtained by thermoforming, in the hot state, a mixture based on...
Syringe serving also as an ampule and associated equipment
A syringe serves also as an ampule and saves labor in transferring contained liquid from an ampule container to a syringe and is not bulky when disposing it. The...
Injection syringe including device for preparation of injection
An injection syringe including a device for preparation of an injection in situ, useful to the injection which is liable to suffer chemical changes if left for a...
Medicinal radioactive ruthenium radiation sources with high dosage rate and
method for producing the same
The invention relates to radioactive ruthenium sources with a dosage rate of at least 1.5 Gy/min at a distance (water) of 2 mm, consisting of an activity carrier...
Two surfactant-containing medicinal composition
Provided is a medicinal composition having a very satisfactory drug release profile and a very satisfactory drug absorption profile after oral administration...
Amphiphilic compounds with at least two hydrophilic and at least two
hydrophobic groups based on di-, oligo- or...
The invention relates to amphiphilic compounds of the general formula (I) with at least two hydrophilic and at least two hydrophobic groups based on di, oligo or...
Method and apparatus for manufacturing tablet capable of quick
disintegration in oral cavity
A method and an apparatus are adapted to manufacture a tablet capable of quick disintegration in the oral cavity that has a sufficiently large porosity and can...
Germination activated red Ganoderma lucidum spores and method for producing
The present invention describes a method for germination activating spores of red Ganoderma lucidum to produce bioactive substances which has medicinal effects...
C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical
A medicinal aerosol steroid solution formulation product with enhanced chemical stability. The steroid is a 20-ketosteroid having an OH group at the C-17 or C-21...
Injection device with bellowed reservoir
Devices for injection of medicines into a human body are designed for one-time use during inpatient or outpatient treatment. The reuse of an injection device...
Addition cross-linking, two-component silicone material with high shore
hardness and high modulus of elasticity
Addition cross-linking two-component silicone materials Addition cross-linking two-component silicone materials on polysiloxane base, especially for the use in...
Propynyl or dienyl biaromatic compounds
The invention relates to novel propynyl or dienyl biaromatic compounds which have the general formula (I) ##STR1## as well as to the use of these compounds in...
Substituted heterocyclic compounds, method for preparing and compositions
The invention relates to compounds of formula (I): ##STR1## wherein: R.sup.1, R.sup.2 and R.sup.3 are as defined in the description, X is as defined in the...
Analogues of camptothecin, preparation procedures, their application as
medicines and the pharmaceutical...
A compound of the formula ##STR1## wherein the substituents are as defined in the specification and a method of inhibiting tumors.
Heterocyclic compounds useful as pharmaceutical agents
Compounds of formula (I) ##STR1## in which all variables are defined in the description and their salts inhibit the enzyme oxido squalene cyclase and are useful...
A class of water insoluble iodophors comprising complexes of iodine with various nylons such as nylon-4,6, nylon-6, nylon-6,6 or other polyamides is disclosed....
Apparatus and method for painless intramuscular or subcutaneous injections
A painless injection apparatus includes a first injector having a first storage chamber storing a numbing agent, a first needle, and a first plunger, and a...
Delivery mechanism for balloons, drugs, stents and other
physical/mechanical agents and method of use
A balloon catheter for use with a guidewire is disclosed. The catheter has a body with a balloon located thereon, preferably at the distal end. A lumen within...
Process for preparing .alpha.-hydroxycarboxylate
There is herein disclosed a process for efficiently preparing, from an .alpha.-hydroxycarboxylic amide and an alcohol in an industrially advantageous manner, an...
Nitric oxide carriers based on polyazamacrocycle complexes
Novel compounds capable of carrying and releasing nitrogen oxide (NO) in a biological medium, their use for implementing a therapeutic treatment method or a...
Indole derivatives and medicinal compositions containing the same
The present invention relates to indole derivatives represented by the general formula: ##STR1## (wherein R represents an ethyl group or a 2,2,2-trifluoroethyl...
The present invention is concerned with a novel benzamide of formula (I). ##STR1## Pharmaceutical compositions comprising said novel compounds, process for ...
Substituted dimeric compounds
The invention relates to compound of formula (I): wherein: A represents a grouping NR.sup.1 C(Q)R.sup.2, C(Q)NR.sup.2 R.sup.3 or NR.sup.1 C(Q)NR.sup.2 R.sup.3, B...
Purine derivatives and medicinal use thereof
A novel purine derivative exhibiting an effect to control inflammatory symptoms characteristic to nephritis and a medicine comprising this compound as an...
Polymerase chain reaction-restriction fragment length polymorphism test for
the authentication of herbal...
This invention provides a procedure for authentication of plant and animal materials used as traditional Chinese medicine is described. This method amplifies and...
Method and device for determining adhesive performance of flat adhesive
products on the skin of humans or mammals
A process for ascertaining the adhesive behaviour of pressure-sensitive adhesive flat materials such as medicinal adhesive tape and, in particular,...
Trifluoro-substituted benzoic acid, esters thereof and processes for
preparing the same
The present invention is to provided a trifluoro-substituted benzoic acid, an ester thereof, particularly 2,3,4-trifluoro-5-iodobenzonic acid, ...
Artemisinin derivatives, method for the preparation thereof and
pharmaceutical compositions containing the same
The invention relates to compound of the general formula (I): wherein: R represents the radical of formula (II): ##STR1## A is as defined in the description, and...
Method for modifying melamine derivatives
The present invention provides a method for modifying melamine derivatives that can produce N-substituted melamine derivatives by introducing a substituent group...
Heavy metal chelating agent for oral administration, its synthesis and its
uses in medicine and health protection
The present invention relates to a new kind of heavy metal chelating agents and a preparation process and uses thereof. The said heavy metal chelating agents are...
Homocysteine desulphurase from the protozoan trichomonas vaginalis
The present invention relates to an assay for determining homocysteine, cysteine, O-acetyl-L-serine and/or methionine levels in a biological sample using an...
Multilayer film and container
The present invention provides a multilayer film comprising five layers, wherein each layer is constituted by a resin having the following density in that order....
Method of increasing concentrations of caffeic acid derivatives and
alkylamides and compositions containing the...
A method of increasing the concentration of caffeic acid derivatives, such as cichoric acid, and the concentration of alkylamides, such as tetraene alkylamides,...
Pellets containing active ingredients protected against degradation in the
rumen of ruminants
The invention relates to a composition, in pellet form, useful for the nutritional and/or medicinal supplementation of ruminants and a method for admixing the...
Composition comprising a carnitine and glutathione, useful to increase the
absorption of glutathione and...
A composition useful for increasing the absorption of glutathione and for synergizing its effects. This composition may take the form of a dietary supplement,...
Infusion pump extruded metal housing with elastomeric end caps
A housing for a medicinal pump, which is sealed to prevent damage due to exposure of the housing to water or other liquids. The housing includes an extruded case...
A resting system comprising a support (5) for supporting a resting means (4) on which a body can rest in relative comfort, wherein a support means (5) is...
Method and apparatus using shaped field of repositionable magnet to guide
Methods and apparatuses for displaying and using a shaped field of a repositionable magnet to move, guide, and/or steer a magnetic seed or catheter in living...
Process for preparing omeprzole
The present invention relates to a novel process for the synthesis of 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benz imidazole, known...
Nucleic acids encoding narbonolide polyketide synthase enzymes from
Host cells comprising recombinant vectors encoding the narbomycin polyketide synthase and narbomycin modification enzymes from Streptomyces narbonensis can be...
Bicycloloactam compounds, use thereof and intermediates for preparing
A bicyclolactam compound of the formula (1) is disclosed, which has an excellent anxiolytic effect, is high in safety, and is useful as an effective component of...
The present invention concerns the compounds of formula ##STR1## the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically...
Therapeutic antimicrobial polypeptides, their use and methods for
A novel class of antimicrobial agents for animal species including cecropins, attacins, lysozymes, phage derived polypeptides, such as those transcribed from...
Holistic method of treating injured or pathologic tissue with a laser
A holistic method of therapeutic laser treatment for body tissues in a problematic area, comprising the following steps: using a laser discharge probe to...