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Substituted piperidine derivative for treating urinary disturbance
Disclosed herein is a substituted piperidine derivative represented by the following general formula (1): ##STR1## wherein R.sup.1 means an aryl or heteroaryl...
Quinuclidine derivatives and medicinal composition thereof
Quinuclidine derivatives represented by general following general formula (I), salts, N-oxides or quaternary ammonium salts thereof, and medicinal compositions...
Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors
Substituted heteroaromatic compounds, and in particular substituted bicyclic heteroaromatic compounds of formula (I), wherein X is N or CH; A represents a fused...
Method for producing L-allysine acetal
A method for producing L-allysine acetal represented by general formula (II), comprising reacting D,L-allysinamide acetal represented by general formula (I) with...
Fluid delivery device with temperature controlled energy source
A fluid delivery apparatus for infusing medicinal fluids into a patient which is of a compact, low profile, laminate construction. The apparatus embodies a novel...
Process for isolating
A process for purifying 2-amino-6-chloro-9-[(1'S,2'R)-1',2'-bis(hydroxymethyl) cycdopropane-1'-yl]methylpurine represented by the following formula (5) ...
Compounds of formula (I): wherein: n is 0 or 1, W represents --CO-- or S(O).sub.r wherein r is 0, 1 or 2, Z represents a group selected from aryl, arylalkyl, heteroaryl...
Pyrrole derivatives and medicinal composition
The invention relates to a pharmaceutical composition comprising a pyrrole derivative of the following formula  or a pharmaceutically acceptable salt thereof,...
Tricyclic compounds having saturated rings and medicinal compositions
containing the same
##STR1## Compounds represented by general formula (I) or their salts, having .beta..sub.3 -adrenoceptor agonism and being efficacious when employed in drugs...
Spiro imidazoline compounds
The invention relates to a compound of formula (I): ##STR1## wherein: A represents an optionally substituted benzene ring, B represents an imidazoline ring of formula...
Quinolinomorphinane derivatives and medicinal use thereof
The present invention provides a quinolinomorphinan derivative or a pharmacologically acceptable acid addition salt thereof, and an agent for curing or...
Formamides as therapeutic agents
A family of compounds having the general structural formula ##STR1## where W is a reverse hydroxamic acid group, and R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5...
This invention relates to an inhalation apparatus for dispensing substances for inhalation and, in particular, but not exclusively, for dispensing medicinal...
Tablet cassette for automatic tablet sorting and counting machine
A tablet cassette for an automatic tablet dispensing system is disclosed. The tablet cassette includes a cylindrical rotor received into a medicine case of the...
Devices and methods for monitoring female arousal
Devices and methods according to embodiments of the invention measure physiological changes that occur in the female during sexual arousal. These include changes...
Medicines for treating dementia or cognitive disorder, which comprises
asiatic acid derivatives
Disclosed is the use of 2-oxoasiatic acid in the treatment of dementia or cognitive disorders.
1-(1,2-Disubstituted piperidinyl)-4-substituted piperidine derivatives
The present invention concerns compounds of formula ##STR1## the N-oxide forms, the pharmaceutically acceptable addition salts and stereochemically isomeric...
Farnesyl protein transferase inhibiting (imidazol-5-yl)methyl-2-quinolinone
This invention comprises the novel compounds of formula (I) ##STR1## wherein the dotted line represents an optional bond; X is oxygen or sulfur; R.sup.1 is...
Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors
Substituted heteroaromatic compounds of formula (A) wherein X is N or CH; in which (a) represents a fused 5, 6 or 7-membered heterocyclic ring and R.sup.3 is a...
Endopeptidase produced by Lactobacillus helveticus
An endopeptidase produced by Lactobacillus helveticus which hydrolyzes peptides with about 3-34 amino acid residues, but not proteins, has been discovered. The...
Unit for orienting and supplying bottom shells of medicinal capsules
A unit for orienting and supplying bottom shells, the unit having a drum rotating about a vertical axis and in turn having a number of seats, each for housing...
Method for recording skin galvanic reactions and device for realizing
In the field of medicine and medical engineering, in particular to methods and devices for diagnostics of the status of an alive organism basing on skin...
4-fluorosalicyclic acid derivative and process for production thereof
The present invention provides a 4-fluorosalicylic acid derivative represented by the following general formula (1): ##STR1## (wherein X.sup.1, X.sup.2 and...
Novel benzimidazole derivatives represented by the formula (I): ##STR1## wherein R.sub.3 is a carboxyl group, a esterified carboxyl group, an amidated...
The present invention relates to novel tetracycline derivatives, to intermediates used in their preparation, to pharmaceutical compositions containing them and...
Compounds with chelation affinity selectivity for first transition
series elements: use in medical therapy and...
This invention involves synthesis and use of a class of compounds with chelation affinity and selectivity for first transition series elements. Administration of...
Use of sericin as antioxidants and tyrosinase inhibitors
This invention relates to a composition useful as an antioxidant or an inhibitor for tyrosinase activity which comprises as an active ingredient a sufficient...
Regulated transcription of targeted genes and other biological events
Dimerization and oligomerization of proteins are general biological control mechanisms that contribute to the activation of cell membrane receptors, ...
Retrievable bioartificial implants having dimensions allowing rapid
diffusion of oxygen and rapid biological...
Bioartificial implants and methods for their manufacture and use are described, particularly bioartificial pancreases. In particular, the implants may be thin...
Audio guided intubation stylet
A intubation stylet having a cylindrical guide member is disclosed wherein the guide member has a proximal end, a distal end, and an intermediate section...
Tamper resistant programmable medicine dispenser
A portable electrically operable and tamper resistant medication dispenser for supplying multiple daily medications to a patient on a predetermined schedule and...
A compound of formula (I) ##STR1## in which: m, and n, which may be identical or different, represent 0 or 1, X and Y, which may be identical or different,...
Crystalline form of the S-enantiomer of omeprazole
The invention provides S-omeprazole in a neutral form characterised in that it is in a solid state, preferably in a partly crystalline or substantially...
Indications for the use as medicaments of multipotent parapox immunity
inducers from attenuated,...
The use is disclosed of multipotent parapox immunity inducers from attenuated, non-immunogenic pox or parapox viruses (pox inducers) to produce medicaments with...
Frozen aqueous solution with nutrients method of packaging and utilizing
The invention encompasses a frozen composition containing an active ingredient. The active ingredients include but are not limited to a nutrient mixture and a...
Disclosed is a poultice capable of rapidly curing an affected part of a patient's body and of enhancing a curative value by increasing an infiltration efficiency...
Acyclovir transdermal delivery system
A transdermal formulation for providing antiviral effect in dermis or epidermis, wherein comprising (a) 0.01 to 30 weight percent of antiviral drug; (b) 0.05 to...
Method and arrangement for photoablation
A method for photoablation in the field of dermatological medicine and to an arrangement for carrying out this method is disclosed in which the laser radiation...
Device for loading a syringe from a vial
A hand held device for loading a hypodermic syringe from a medicine vial is configured for easy placement of the syringe into a closely conforming channel in the...
Shock absorbing cushion structures are disclosed which are formed by upper and lower sheets peripherally sealed and formed to define a series of ...
Trifluoro-substituted benzoic acid, esters thereof, and process for
producing the same
The present invention is to provide a trifluoro-substituted benzoic acid, an ester thereof, particularly 2,3,4-trifluoro-5-iodobenzoic acid, ...
Bicyclolactam compounds, use thereof and intermediates for preparing
A bicyclolactam compound of the formula (1) is disclosed, which has an excellent anxiolytic effect, is high in safety, and is useful as an effective component of...
2,4-diaminopyrimidine derivates as dopamine D4 receptor antagonist
The present invention concerns the compounds of formula ##STR1## the N-oxide forms, the pharmaceutically acceptable acid addition salts and stereochemically...
Fluid delivery apparatus with flow indicator and vial fill
An apparatus for accurately infusing medicinal agents into an ambulatory patient at specific rates over extended periods of time. The apparatus is of a compact,...
Screw rotor set
Known designs of single-thread screw rotors in single-piece cast iron constructions having wrap angles of >720 degrees with balancing cavities on the face of...
Method and apparatus using shaped field of repositionable magnet to
Methods and apparatuses for displaying and using a shaped field of a repositionable magnet to move, guide, and/or steer a magnetic seed or catheter in living...
Indolomorphinan derivative and agent for curing and preventing cerebral
The present invention provides an indolomorphinan derivative or a pharmacologically acceptable acid addition salt thereof, and an agent for curing and preventing...
The present invention concerns the compounds of formula ##STR1## the N-oxides, the pharmaceutically acceptable addition salts and the stereochemically...
Monomers with dilactone cycle, and corresponding polymers
The invention concerns monomers with dilactonic cycle and the corresponding polymers, their preparation, and materials containing these polymers. The monomers...