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Antagonistic peptides for frizzled-1 and frizzled-2
The invention is in the field of molecular medicine. It provides antagonistic compounds for frizzled 1 and/or frizzled-2 receptors, which may be useful in...
This invention relates to polypeptides which bind to EGFR family receptors and to applications of those polypeptides in medicine, veterinary medicine, diagnosis...
Herbal combinations for treatment of a skin condition
A method and medicine for treating melanoma, BCC (basal cyr carcinoma) or psoriasis or other inflammatory skin disease, or a combination thereof, comprising...
Fully human anti-TNF-alpha monoclonal antibody, preparation method and use
The present invention provides a full human anti-TNF-.alpha. monoclonal antibody, the preparation method and use thereof. The antibody in the present invention...
Interferon alpha-2a modified by polyethylene glycol and methods of
The present invention relates to interferon (IFN)-.alpha.2a modified at a specific Lys residue with Y-shaped branched polyethylene glycol (PEG) derivative and...
Method for deactivating undesired contaminations in leech extracts
The present invention provides a method for inactivating viruses and/or bacteria in medicinal-leech extracts by means of electromagnetic radiation.
Swallowable multi-nozzle dosing device for releasing medicines in the
A capsule and methodology for dispensing a medicament in the gastrointestinal tract of a mammal is disclosed, the gastrointestinal tract having tissue sites of...
Medication mixing device and medication mixing method
A medicine mixing device includes a pedestal, a main rotating-base, a sub rotating-base, and a control unit. The pedestal is used to place medicine containers...
Laser system for treatment of the eye
Sulfonamide derivatives as Nav 1.7 inhibitors
This invention relates to sulfonamide derivative of formula (I), to their use in medicine, to compositions containing them, to processes for their preparation,...
H5 proteins, nucleic acid molecules and vectors encoding for those, and
their medicinal use
The present invention relates to novel hemagglutinin H5 proteins, nucleic acids and vectors encoding for those as well as vaccines comprising any of such H5...
Process for the preparation or purification of olmesartan medoxomil
The present invention relates to a process for the preparation and purification of olmesartan medoxomil hydrohalide salts and optionally converting them to...
Substituted indolyl alkyl amino derivatives as novel inhibitors of histone
This invention comprises the novel compounds of formula (I) ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3, X and Y have defined meanings, having histone...
Composition for preventing and treating influenza-virus-induced diseases
The present invention relates to a medicinal extract useful for preventing and treating influenza-virus-induced diseases, and to a pharmaceutical composition...
Methods, systems, and apparatus for obtaining biofuel from coffee and
fuels produced therefrom
In some embodiments, the present disclosure provides a method for producing biofuel from a feedstock that includes one or more coffee sources, such as green...
Method for managing obesity, diabetes and other glucose-spike-induced
Disclosed is a method for managing diabetes by reducing the post-prandial blood glucose spike, or the glucose shock. The blood glucose spike, or the glucose...
Aminopyrazine derivative and medicine
The present invention relates to a compound represented by general formula  satisfying the following (I) or (II), or a pharmaceutically acceptable salt of...
Therapies for cancer using RLIP76
The present invention is a composition identified as a region of ralA binding protein 1, wherein the region neighbors a membrane-associated portion of the ralA...
Method of determining a chemotherapeutic regimen based on ERCC1 and TS
The present invention relates to prognostic methods which are useful in medicine, particularly cancer chemotherapy. The object of the invention to provide a...
Extracts of Chenopodium ambrosioides L., the compositions comprising said
extracts, the preparing process and...
The present invention relates to plant extracts, specifically, the extracts of Chinese medicine Chenopodium ambrosioides L. and the composition comprising...
Fulvestrant nanosphere/microsphere and preparative method and use thereof
Fulvestrant nanosphere/microsphere and preparation method and use thereof are provided in the present invention. The carrier material of the fulvestrant...
Use of alkaline phosphatase in the treatment of reduced renal function
The invention relates to the field of medicine and in particular to the use of alkaline phosphatase in the treatment of renal diseases, such as reduced renal...
Dispensing fluid from an infusion pump system
Some embodiments of an infusion pump system include a drive system that advances a piston rod to dispense medicine to a user. Moreover, the drive system can be...
Thumbwheel-operated device including a cover for opening and closing a
A device for selectively allowing and disallowing passage of semi-solid from a container. A housing has an inlet port through which semi-solid can enter, an...
Modular door mounted climate controlled medicine compartment
An appliance system includes at least an appliance and a module. The appliance door(s) have an exterior surface and an interior surface having a door liner. The...
Medicine packing apparatus
A tablet supply unit (2) of a medicine packing apparatus (1) has a tablet housing section (22c) including tablet housing chambers (21) for respectively housing...
Methods for stratifying and annotating cancer drug treatment options
Personalized medicine involves the use of a patient's molecular markers to guide treatment regimens for the patient. The scientific literature provides multiple...
Synthesis of enone intermediate
The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the...
Derivatives of azaindoles as inhibitors of protein kinases ABL and SRC
The present invention relates to compounds of general formula I and use thereof as inhibitors of protein kinases AbI and Src and the method of production...
Low hygroscopic aripiprazole drug substance and processes for the
The present invention provides low hygroscopic forms of aripiprazole and processes for the preparation thereof which will not convert to a hydrate or lose their...
Topical compositions comprising fermented extracts of traditional chinese
medicinal (TCM) ingredients, and...
The present invention relates to topical compositions containing fermented extracts of Traditional Chinese Medicinal (TCM) ingredients for improving the...
Provided is a medicated patch containing a medicinal agent and an adhesive base material and having an acid value of no greater than 28, where the medicinal...
Systems and methods for administering medication
The syringe systems disclosed herein provide in part devices for allowing patients with comprised joint strength to more easily administer medicine. Certain...
The present invention relates to a patch, which can be used to secure catheters, wound drainage devices, and/or drug delivery devices, when said catheter and...
Nuclear medicine imaging system and method using multiple types of imaging
A Nuclear Medicine (NM) imaging system and method using multiple types of imaging detectors are provided. One NM imaging system includes a gantry, at least a...
The invention relates to compounds represented by the general formula (I) and the like. In the formula, Ar.sup.1 denotes an aryl or heteroaryl group which may...
Aminocarboxylic acid derivative and medicinal use thereof
The present invention relates to a compound represented by the formula (I), a salt thereof, an N-oxide form thereof, a solvate thereof, or a prodrug thereof,...
Therapeutic applications of p53 isoforms in regenerative medicine, aging
The present invention provides methods and compositions for modulating cell senescence and cell proliferation using isoforms of the p53 tumor suppressor...
Tc and Re labeled radioactive glycosylated octreotide derivatives
Improved sst-receptor binding peptidic ligands for diagnostic and therapeutic applications in nuclear medicine are provided. The improved ligands contain either...
Huperzia serrata (Thunb.) Trev. composition comprising compounded
Huperzine A and Huperzine B and methods for...
The invention is directed to the field of natural medicine, specifically to alkaloid extracts of Huperzia serrata (Thunb.) Trev. A Huperzia serrata (Thunb.)...
Bi-stable quantum wire array of self-assembled nanomedicine and the
preparation method therefor
A bi-stable quantum wire array of self-assembled nano-medicine and its process present in the invention. The bi-stable quantum wire array with quantum bit and...
Metering device for the inhalation of a pulverulent substance
A dosing device can be activated by a vacuum air stream of a user for the inhalation of a powder substance, particularly medicine, which is arranged in a supply...
Nebulizer having flow meter function
In accordance with non-limiting examples, a nebulizer includes a main body comprising an air channel section and further comprising a mixing chamber and a...
A portable cooler has a thermally isolating outer shell defining an internal compartment for holding contents to be kept cool, such as, for example, food,...
Apparatus and method to apply substances to tissue
Methods and apparatuses to apply substances to a biological tissue are described. The tissue having an target below a surface is stretched to provide openings...
Engineered pertactin variants for vaccine use
The present invention is related with the field of Biomedicine. It comprises the engineering of the Pertactin protein (Prn) and using it as part of bacterial...
Forms of rifaximin and uses thereof
The present invention relates to Rifaximin polymorphic forms, to their use in medicinal preparations and to therapeutic methods using them.
Dihydrobenzoxathiazepine compounds, a process for their preparation and
pharmaceutical compositions containing them
Compounds of formula (I): ##STR00001## wherein R.sub.1 represents a hydrogen atom or a heterocyclic, cyano, alkoxycarbonyl, alkylsulphonylaminoalkyl or...
Diphenyl sulfide derivatives and medicines containing same as active
Provided are diphenyl sulfide derivatives which have excellent S1P3 antagonistic activity and are useful as drugs. Intensive studies have been made for the...
Tetracyclic tetrahydrofuran derivatives containing cyclic amine side chain
This invention concerns novel substituted tetracyclic tetrahydrofuran derivatives containing a cyclic amine side chain with binding affinities towards dopamine...